caa a22 4500 445340789 CHVBK 20180317142812.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00436-011-2430-4 doi (NATIONALLICENCE)springer-10.1007/s00436-011-2430-4 The composition of upstream open reading frames (uORF) in four genes from Trypanosoma cruzi typical strains [Elektronische Daten] [Lauren Jaeger, Adeilton Brandão] Upstream open reading frames (uORF) are small open reading frames located in the 5′ untranslated region (5′ utr) of a mature mRNA. We analysed in four strains representing the Trypanosoma cruzi groups Tc I, Tc II, Tc IV and Tc VI the uORF present in 5′ utr sequences of four genes: P-type H+-ATPase 1, DEAD/H RNA helicase, casein kinase 1.1 and ferredoxin-NADP+ reductase. A segment in the 5′ utr at each of these genes encompassing one or more uORF was PCR amplified and sequenced. An analysis of these sequences reveals that the uORF in T. cruzi show minor variations; however, these nucleotide substitutions mirror the divergence of T. cruzi strains into major groups. Springer-Verlag, 2011 Jaeger Lauren Laboratory of Interdisciplinary Medical Researches, Instituto Oswaldo Cruz, Fiocruz Av. Brasil 4365, 21040-360, Rio de Janeiro, Brazil aut Brandão Adeilton Laboratory of Interdisciplinary Medical Researches, Instituto Oswaldo Cruz, Fiocruz Av. Brasil 4365, 21040-360, Rio de Janeiro, Brazil aut Parasitology Research Springer-Verlag 109/4(2011-10-01), 1205-1208 0932-0113 109:4<1205 2011 109 436 https://doi.org/10.1007/s00436-011-2430-4 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00436-011-2430-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jaeger Lauren Laboratory of Interdisciplinary Medical Researches, Instituto Oswaldo Cruz, Fiocruz Av. Brasil 4365, 21040-360, Rio de Janeiro, Brazil aut NATIONALLICENCE 700 1- Brandão Adeilton Laboratory of Interdisciplinary Medical Researches, Instituto Oswaldo Cruz, Fiocruz Av. Brasil 4365, 21040-360, Rio de Janeiro, Brazil aut NATIONALLICENCE 773 0- Parasitology Research Springer-Verlag 109/4(2011-10-01), 1205-1208 0932-0113 109:4<1205 2011 109 436 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer