caa a22 4500 445340991 CHVBK 20180317142812.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00436-011-2379-3 doi (NATIONALLICENCE)springer-10.1007/s00436-011-2379-3 Further evaluation in field tests of the activity of three anthelmintics (fenbendazole, oxibendazole, and pyrantel pamoate) against the ascarid Parascaris equorum in horse foals on eight farms in Central Kentucky (2009-2010) [Elektronische Daten] [Eugene Lyons, Sharon Tolliver, Tetiana Kuzmina, Sandra Collins] The activity of three anthelmintics (fenbendazole-FBZ; oxibendazole-OBZ; and pyrantel pamoate-PRT) was ascertained against the ascarid Parascaris equorum in horse foals on eight farms in Central Kentucky (2009-2010) in field tests. A total of 316 foals were treated, and 168 (53.2%) were passing ascarid eggs on the day of treatment. Evaluation of drug efficacy was determined qualitatively by comparing the number of foals passing ascarid eggs in their feces before and after treatment. The main purpose was to obtain data on current activity of these compounds against ascarids. Additionally, the objective was to compare these findings with those from earlier data on the efficacy of these three compounds on nematodes in foals in this geographical area. Efficacies (average) for the foals ranged for FBZ (10mg/kg) from 50% to 100% (80%), for OBZ (10mg/kg) from 75% to 100% (97%), and for PRT at 1× (6.6mg base/kg) from 0% to 71% (2%) and at 2× (13.2mg base/kg) 0% to 0% (0%). Although the efficacy varied among the drugs, combined data for all farms indicated a significant reduction of ascarid infections for FBZ (p < 0.0001) and OBZ (p < 0.0001) but not for PRT (p = 0.0953). Springer-Verlag, 2011 Lyons Eugene Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, 40546-0099, Lexington, KY, USA aut Tolliver Sharon Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, 40546-0099, Lexington, KY, USA aut Kuzmina Tetiana I.I. Schmalhausen Institute of Zoology, vul. B. Khmelnytskogo, 15, 01601, Kiev, Ukraine aut Collins Sandra Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, 40546-0099, Lexington, KY, USA aut Parasitology Research Springer-Verlag 109/4(2011-10-01), 1193-1197 0932-0113 109:4<1193 2011 109 436 https://doi.org/10.1007/s00436-011-2379-3 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00436-011-2379-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lyons Eugene Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, 40546-0099, Lexington, KY, USA aut NATIONALLICENCE 700 1- Tolliver Sharon Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, 40546-0099, Lexington, KY, USA aut NATIONALLICENCE 700 1- Kuzmina Tetiana I.I. Schmalhausen Institute of Zoology, vul. B. Khmelnytskogo, 15, 01601, Kiev, Ukraine aut NATIONALLICENCE 700 1- Collins Sandra Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, 40546-0099, Lexington, KY, USA aut NATIONALLICENCE 773 0- Parasitology Research Springer-Verlag 109/4(2011-10-01), 1193-1197 0932-0113 109:4<1193 2011 109 436 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer