caa a22 4500 445343680 CHVBK 20180317142822.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00406-010-0118-x doi (NATIONALLICENCE)springer-10.1007/s00406-010-0118-x The prevalence and clinical correlates of metabolic syndrome in patients with schizophrenia: findings from a cohort in Turkey [Elektronische Daten] [M. Yazıcı, A. Anıl Yağcıoğlu, A. Ertuğrul, N. Eni, S. Karahan, E. Karaağaoğlu, S. Tokgözoğlu] Most studies point to an increased prevalence of metabolic syndrome (MS) and an increased risk of coronary heart disease (CHD) in schizophrenia patients with MS. The aims of this study were to compare the prevalence of MS in schizophrenia patients with the general population, to explore the clinical correlates and predictors of MS and to evaluate the risk for CHD within 10years. Consecutive 319 patients, aged 18-75years, with a diagnosis of schizophrenia according to the DSM-IV were enrolled. The ATP-III, the ATP-IIIA and the IDF criteria were used to define MS. 10-year risk of CHD events was calculated with the Framingham score. One hundred nine (34.2%) patients met the ATP-III criteria, 118 (37%) the ATP-IIIA and 133 (41.7%) the IDF criteria for MS. Patients with MS were older, had a later onset of illness and an older age at first hospitalization. The prevalence of MS in schizophrenia patients was higher from the general population only within the 20-29 age group. Patients with MS had a higher age and sex-corrected 10-year risk of CHD events. The only predictor of MS was the age of illness onset. In conclusion, countries where the general population prevalence of MS is already too high, schizophrenia patients younger than 30years of age might be under higher risk of morbidity and mortality related with MS. This study points to the necessity for aggressive interventions to correct MS in schizophrenia as early as possible, within the first 10years of post detection. Springer-Verlag, 2010 Metabolic syndrome nationallicence Schizophrenia nationallicence Prevalence nationallicence Correlates nationallicence Cardiovascular risk nationallicence Yazıcı M. Department of Psychiatry, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut Anıl Yağcıoğlu A. Department of Psychiatry, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut Ertuğrul A. Department of Psychiatry, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut Eni N. Department of Psychiatry, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut Karahan S. Department of Biostatistics, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut Karaağaoğlu E. Department of Biostatistics, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut Tokgözoğlu S. Department of Cardiology, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut European Archives of Psychiatry and Clinical Neuroscience Springer-Verlag 261/1(2011-02-01), 69-78 0940-1334 261:1<69 2011 261 406 https://doi.org/10.1007/s00406-010-0118-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00406-010-0118-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yazıcı M. Department of Psychiatry, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Anıl Yağcıoğlu A. Department of Psychiatry, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Ertuğrul A. Department of Psychiatry, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Eni N. Department of Psychiatry, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Karahan S. Department of Biostatistics, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Karaağaoğlu E. Department of Biostatistics, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Tokgözoğlu S. Department of Cardiology, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey aut NATIONALLICENCE 773 0- European Archives of Psychiatry and Clinical Neuroscience Springer-Verlag 261/1(2011-02-01), 69-78 0940-1334 261:1<69 2011 261 406 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer