caa a22 4500 44534430X CHVBK 20180317142824.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00406-010-0141-y doi (NATIONALLICENCE)springer-10.1007/s00406-010-0141-y Severity of alcohol-related problems and mortality: results from a 20-year prospective epidemiological community study [Elektronische Daten] [Manfred Fichter, Norbert Quadflieg, Uwe Fischer] There is evidence that high alcohol use is associated with an increase in mortality. Little is known about long-term effects of problematic alcohol consumption in non-clinical (community) populations. The aim of our study was to obtain data on this and related issues in a representative rural community sample assessed longitudinally over a period of 20years. Assessments focused on a baseline survey from 1980 to 1984 and 20-year follow-up from 2001 to 2004. Based on expert interviews and standardized self-rating scales (e.g. MALT; Munich Alcoholism Test), the following three groups were defined (a) severe alcohol problems, (b) moderate alcohol problems, and (c) no alcohol problems. Mortality and hazard rates were analyzed with logistic and Cox regression adjusted for several health risk factors. From an original community sample of 1,465 individuals, 448 were deceased at 20-year follow-up. Participation rates were high. Baseline prevalence according to the MALT was 1.6% for severe alcohol problems and 4.0% for moderate alcohol problems. Over the 20-year time span, individuals with severe alcohol problems had a significantly elevated risk for dying earlier than the group with no alcohol problems (2.4 times higher). Mortality for those with moderate alcohol problems at baseline had a non-significantly elevated 20-year mortality risk (1.5 times higher) compared to those with no alcohol problems. Cox survival analyses corroborate these findings from multiple sequential logistic regression analyses. In discussing the mortality risk of persons with alcohol problems, the severity of the alcohol problems must be taken into account. Springer-Verlag, 2010 Psychiatric epidemiology nationallicence Alcoholism nationallicence Mortality nationallicence Prospective longitudinal community studies nationallicence Fichter Manfred Department of Psychiatry, University of Munich (LMU), 80336, Munich, Germany aut Quadflieg Norbert Department of Psychiatry, University of Munich (LMU), 80336, Munich, Germany aut Fischer Uwe Department of Psychiatry, University of Munich (LMU), 80336, Munich, Germany aut European Archives of Psychiatry and Clinical Neuroscience Springer-Verlag 261/4(2011-06-01), 293-302 0940-1334 261:4<293 2011 261 406 https://doi.org/10.1007/s00406-010-0141-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00406-010-0141-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fichter Manfred Department of Psychiatry, University of Munich (LMU), 80336, Munich, Germany aut NATIONALLICENCE 700 1- Quadflieg Norbert Department of Psychiatry, University of Munich (LMU), 80336, Munich, Germany aut NATIONALLICENCE 700 1- Fischer Uwe Department of Psychiatry, University of Munich (LMU), 80336, Munich, Germany aut NATIONALLICENCE 773 0- European Archives of Psychiatry and Clinical Neuroscience Springer-Verlag 261/4(2011-06-01), 293-302 0940-1334 261:4<293 2011 261 406 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer