caa a22 4500 445350644 CHVBK 20180317142842.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00221-011-2863-0 doi (NATIONALLICENCE)springer-10.1007/s00221-011-2863-0 Both sleep and wakefulness support consolidation of continuous, goal-directed, visuomotor skill [Elektronische Daten] [Michael Borich, Teresa Kimberley] Sleep has been shown to benefit memory consolidation for certain motor skills, but it remains unclear if this relationship exists for motor skills with direct rehabilitation applications. We aimed to determine the neurobehavioral relationship between finger-tracking skill development and sleep following skill training in young, healthy subjects. Forty subjects received tracking training in the morning (n=20) or the evening (n=20). Measures of tracking skill and cortical excitability were collected before and after training. Following training, tracking skill and measures of cortical excitability were assessed at two additional follow-up visits (12 and 24h post-training) for each subject following an episode of sleep or waking activity. Two-way repeated-measures ANOVAs with Bonferroni-adjusted post hoc tests were conducted for tracking accuracy and measures of cortical excitability. Skill performance improved after training and continued to develop offline during the first post-training interval (12h). This development was not further enhanced by sleep during this interval. Level of skill improvement was maintained for at least one day in both training groups. Cortical excitability was reduced following training and was related to level of skill performance at follow-up assessment. These data suggest offline memory consolidation of a continuous, visuospatial, finger-tracking skill is not dependent on sleep. These findings are in agreement with recent literature, indicating characteristics of a motor skill may be sensitive to the beneficial effect of sleep on post-training information processing. Springer-Verlag, 2011 Sleep nationallicence Motor learning nationallicence Transcranial magnetic stimulation nationallicence Excitability nationallicence Primary motor cortex nationallicence Memory consolidation nationallicence Borich Michael Department of Physical Medicine and Rehabilitation, Program in Physical Therapy/Rehabilitation Science, University of Minnesota, Minneapolis, MN, USA aut Kimberley Teresa Department of Physical Medicine and Rehabilitation, Program in Physical Therapy/Rehabilitation Science, University of Minnesota, Minneapolis, MN, USA aut Experimental Brain Research Springer-Verlag 214/4(2011-10-01), 619-630 0014-4819 214:4<619 2011 214 221 https://doi.org/10.1007/s00221-011-2863-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00221-011-2863-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Borich Michael Department of Physical Medicine and Rehabilitation, Program in Physical Therapy/Rehabilitation Science, University of Minnesota, Minneapolis, MN, USA aut NATIONALLICENCE 700 1- Kimberley Teresa Department of Physical Medicine and Rehabilitation, Program in Physical Therapy/Rehabilitation Science, University of Minnesota, Minneapolis, MN, USA aut NATIONALLICENCE 773 0- Experimental Brain Research Springer-Verlag 214/4(2011-10-01), 619-630 0014-4819 214:4<619 2011 214 221 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer