caa a22 4500 445350849 CHVBK 20180317142843.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s00221-011-2569-3 doi (NATIONALLICENCE)springer-10.1007/s00221-011-2569-3 Intrinsic membrane properties of central vestibular neurons in rodents [Elektronische Daten] [Daniel Eugène, Erwin Idoux, Mathieu Beraneck, L. Moore, Pierre-Paul Vidal] Numerous studies in rodents have shown that the functional efficacy of several neurotransmitter receptors and the intrinsic membrane excitability of central vestibular neurons, as well as the organization of synaptic connections within and between vestibular nuclei can be modified during postnatal development, after a lesion of peripheral vestibular organs or in vestibular-deficient mutant animals. This review mainly focuses on the intrinsic membrane properties of neurons of the medial vestibular nuclei of rodents, their postnatal maturation, and changes following experimental or congenital alterations in vestibular inputs. It also presents the concomitant modifications in the distribution of these neurons into different neuron types, which has been based on their membrane properties in relation to their anatomical, biochemical, or functional properties. The main points discussed in this review are that (1) the intrinsic membrane properties can be used to distinguish between two dominant types of neurons, (2) the system remains plastic throughout the whole life of the animal, and finally, (3) the intracellular calcium concentration has a major effect on the intrinsic membrane properties of central vestibular neurons. Springer-Verlag, 2011 Vestibular neuron nationallicence Intrinsic membrane properties nationallicence Postnatal development nationallicence Labyrinthectomy nationallicence Mutant animals nationallicence Intracellular calcium nationallicence Eugène Daniel Centre d'Etudes de la SensoriMotricité (CESeM), UMR 8194, CNRS, Université Paris Descartes, 45 rue des Saints-Pères, 75270, Paris cedex 06, France aut Idoux Erwin Centre d'Etudes de la SensoriMotricité (CESeM), UMR 8194, CNRS, Université Paris Descartes, 45 rue des Saints-Pères, 75270, Paris cedex 06, France aut Beraneck Mathieu Centre d'Etudes de la SensoriMotricité (CESeM), UMR 8194, CNRS, Université Paris Descartes, 45 rue des Saints-Pères, 75270, Paris cedex 06, France aut Moore L. Centre d'Etudes de la SensoriMotricité (CESeM), UMR 8194, CNRS, Université Paris Descartes, 45 rue des Saints-Pères, 75270, Paris cedex 06, France aut Vidal Pierre-Paul Centre d'Etudes de la SensoriMotricité (CESeM), UMR 8194, CNRS, Université Paris Descartes, 45 rue des Saints-Pères, 75270, Paris cedex 06, France aut Experimental Brain Research Springer-Verlag 210/3-4(2011-05-01), 423-436 0014-4819 210:3-4<423 2011 210 221 https://doi.org/10.1007/s00221-011-2569-3 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00221-011-2569-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Eugène Daniel Centre d'Etudes de la SensoriMotricité (CESeM), UMR 8194, CNRS, Université Paris Descartes, 45 rue des Saints-Pères, 75270, Paris cedex 06, France aut NATIONALLICENCE 700 1- Idoux Erwin Centre d'Etudes de la SensoriMotricité (CESeM), UMR 8194, CNRS, Université Paris Descartes, 45 rue des Saints-Pères, 75270, Paris cedex 06, France aut NATIONALLICENCE 700 1- Beraneck Mathieu Centre d'Etudes de la SensoriMotricité (CESeM), UMR 8194, CNRS, Université Paris Descartes, 45 rue des Saints-Pères, 75270, Paris cedex 06, France aut NATIONALLICENCE 700 1- Moore L. Centre d'Etudes de la SensoriMotricité (CESeM), UMR 8194, CNRS, Université Paris Descartes, 45 rue des Saints-Pères, 75270, Paris cedex 06, France aut NATIONALLICENCE 700 1- Vidal Pierre-Paul Centre d'Etudes de la SensoriMotricité (CESeM), UMR 8194, CNRS, Université Paris Descartes, 45 rue des Saints-Pères, 75270, Paris cedex 06, France aut NATIONALLICENCE 773 0- Experimental Brain Research Springer-Verlag 210/3-4(2011-05-01), 423-436 0014-4819 210:3-4<423 2011 210 221 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer