caa a22 4500 445351012 CHVBK 20180317142844.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s00221-010-2499-5 doi (NATIONALLICENCE)springer-10.1007/s00221-010-2499-5 Vestibular primary afferent responses to sound and vibration in the guinea pig [Elektronische Daten] [Ian Curthoys, Vedran Vulovic] This study tested whether air-conducted sound and bone-conducted vibration activated primary vestibular afferent neurons and whether, at low levels, such stimuli are specific to particular vestibular sense organs. In response to 500Hz bone-conducted vibration or 500Hz air-conducted sound, primary vestibular afferent neurons in the guinea pig fall into one of two categories--some neurons show no measurable change in firing up to 2g peak-to-peak or 140dB SPL. These are semicircular canal neurons (regular or irregular) and regular otolith neurons. In sharp contrast, otolith irregular neurons show high sensitivity: a steep increase in firing as stimulus intensity is increased. These sensitive neurons typically, but not invariably, were activated by both bone-conducted vibration and air-conducted sound, they originate from both the utricular and saccular maculae, and their sensitivity underpins new clinical tests of otolith function. Springer-Verlag, 2010 Vestibular nationallicence Utricular nationallicence Saccular nationallicence Otolithic nationallicence Bone conduction nationallicence Sound nationallicence Vibration nationallicence ACS : Air-conducted sound nationallicence ABR : Auditory brainstem response nationallicence BCV : Bone-conducted vibration nationallicence B-71 : The standard clinical bone conduction oscillator (Radioear B71) nationallicence CV* : Normalized coefficient of variation nationallicence Curthoys Ian Vestibular Research Laboratory, School of Psychology, A 18, The University of Sydney, NSW, 2006, Sydney, Australia aut Vulovic Vedran Vestibular Research Laboratory, School of Psychology, A 18, The University of Sydney, NSW, 2006, Sydney, Australia aut Experimental Brain Research Springer-Verlag 210/3-4(2011-05-01), 347-352 0014-4819 210:3-4<347 2011 210 221 https://doi.org/10.1007/s00221-010-2499-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00221-010-2499-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Curthoys Ian Vestibular Research Laboratory, School of Psychology, A 18, The University of Sydney, NSW, 2006, Sydney, Australia aut NATIONALLICENCE 700 1- Vulovic Vedran Vestibular Research Laboratory, School of Psychology, A 18, The University of Sydney, NSW, 2006, Sydney, Australia aut NATIONALLICENCE 773 0- Experimental Brain Research Springer-Verlag 210/3-4(2011-05-01), 347-352 0014-4819 210:3-4<347 2011 210 221 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer