caa a22 4500 445351071 CHVBK 20180317142844.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s00221-011-2554-x doi (NATIONALLICENCE)springer-10.1007/s00221-011-2554-x Temporal binding of auditory and rotational stimuli [Elektronische Daten] [Mark Sanders, Nai-Yuan Chang, Meghan Hiss, Rosalie Uchanski, Timothy Hullar] Integration of cues from multiple sensory channels improves our ability to sense and respond to stimuli. Cues arising from a single event may arrive at the brain asynchronously, requiring them to be "bound” in time. The perceptual asynchrony between vestibular and auditory stimuli has been reported to be several times greater than other stimulus pairs. However, these data were collected using electrically evoked vestibular stimuli, which may not provide similar results to those obtained using actual head rotations. Here, we tested whether auditory stimuli and vestibular stimuli consisting of physiologically relevant mechanical rotations are perceived with asynchronies consistent with other sensory systems. We rotated 14 normal subjects about the earth-vertical axis over a raised-cosine trajectory (0.5Hz, peak velocity 10deg/s) while isolated from external noise and light. This trajectory minimized any input from extravestibular sources such as proprioception. An 800-Hz, 10-ms auditory tone was presented at stimulus onset asynchronies ranging from 200ms before to 700ms after the onset of motion. After each trial, subjects reported whether the stimuli were "simultaneous” or "not simultaneous.” The experiment was repeated, with subjects reporting whether the tone or rotation came first. After correction for the time the rotational stimulus took to reach vestibular perceptual threshold, asynchronies spanned from −41ms (auditory stimulus leading vestibular) to 91ms (vestibular stimulus leading auditory). These values are significantly lower than those previously reported for stimulus pairs involving electrically evoked vestibular stimuli and are more consistent with timing relationships between pairs of non-vestibular stimuli. Springer-Verlag, 2011 Binding nationallicence Vestibular nationallicence Auditory nationallicence Multisensory nationallicence Temporal nationallicence Integration nationallicence Psychophysics nationallicence Synchrony nationallicence Sanders Mark Speech and Hearing Science, Arizona State University, Tempe, AZ, USA aut Chang Nai-Yuan Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA aut Hiss Meghan Speech and Hearing Science, The Ohio State University, Columbus, OH, USA aut Uchanski Rosalie Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA aut Hullar Timothy Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA aut Experimental Brain Research Springer-Verlag 210/3-4(2011-05-01), 539-547 0014-4819 210:3-4<539 2011 210 221 https://doi.org/10.1007/s00221-011-2554-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00221-011-2554-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sanders Mark Speech and Hearing Science, Arizona State University, Tempe, AZ, USA aut NATIONALLICENCE 700 1- Chang Nai-Yuan Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA aut NATIONALLICENCE 700 1- Hiss Meghan Speech and Hearing Science, The Ohio State University, Columbus, OH, USA aut NATIONALLICENCE 700 1- Uchanski Rosalie Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA aut NATIONALLICENCE 700 1- Hullar Timothy Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA aut NATIONALLICENCE 773 0- Experimental Brain Research Springer-Verlag 210/3-4(2011-05-01), 539-547 0014-4819 210:3-4<539 2011 210 221 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer