caa a22 4500 445351292 CHVBK 20180317142844.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00221-011-2626-y doi (NATIONALLICENCE)springer-10.1007/s00221-011-2626-y TMS-induced blinking assessed with high-speed video: optical disruption of visual perception [Elektronische Daten] [Erik Corthout, Mark Hallett, Alan Cowey] It is known that TMS can induce blinking, but it is unknown to what extent and at what time TMS-induced blinking can cover the pupil. We applied single-pulse TMS with a leftward and rightward monophasic current through a round coil over the occipital pole in 8 healthy subjects, using high-speed video to monitor left or right eye with a spatial resolution of 0.1mm and a temporal resolution of 2ms. We plotted eyelid position relative to upper and lower pupil borders as a function of time after TMS for each subject and current direction. We found 2 blinks in every subject, an isolated late blink with one current direction and a superimposed early and late blink with the other current direction, in accordance with our previously reported association between a leftward and rightward lower coil rim current and an early blink in right and left eye, respectively. Blink extent varied, but 4 subjects showed total pupil covering with both current directions. Blink timing varied, but pupil covering was initiated as early as 32ms after TMS and pupil uncovering was completed as late as 200ms after TMS. We found no saccades. We conclude that TMS can cause an important optical disruption of visual perception. Springer-Verlag, 2011 Blinking nationallicence Video recording nationallicence Kinematics nationallicence Pupil nationallicence Transcranial magnetic stimulation (TMS) nationallicence Corthout Erik Department of Experimental Psychology, University of Oxford, South Parks Road, OX1 3UD, Oxford, UK aut Hallett Mark Human Motor Control Section, Medical Neurology Branch, NINDS, National Institutes of Health, Building 10, Room 7D37, 10 Center Drive, 20892-1428, Bethesda, MD, USA aut Cowey Alan Department of Experimental Psychology, University of Oxford, South Parks Road, OX1 3UD, Oxford, UK aut Experimental Brain Research Springer-Verlag 210/2(2011-04-01), 243-250 0014-4819 210:2<243 2011 210 221 https://doi.org/10.1007/s00221-011-2626-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00221-011-2626-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Corthout Erik Department of Experimental Psychology, University of Oxford, South Parks Road, OX1 3UD, Oxford, UK aut NATIONALLICENCE 700 1- Hallett Mark Human Motor Control Section, Medical Neurology Branch, NINDS, National Institutes of Health, Building 10, Room 7D37, 10 Center Drive, 20892-1428, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Cowey Alan Department of Experimental Psychology, University of Oxford, South Parks Road, OX1 3UD, Oxford, UK aut NATIONALLICENCE 773 0- Experimental Brain Research Springer-Verlag 210/2(2011-04-01), 243-250 0014-4819 210:2<243 2011 210 221 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer