caa a22 4500 445351829 CHVBK 20180317142846.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s00221-011-2635-x doi (NATIONALLICENCE)springer-10.1007/s00221-011-2635-x Effect of weight-related labels on corticospinal excitability during observation of grasping: a TMS study [Elektronische Daten] [Patrice Senot, Alessandro D'Ausilio, Michele Franca, Luana Caselli, Laila Craighero, Luciano Fadiga] Recent studies of corticospinal excitability during observation of grasping and lifting of objects of different weight have highlighted the role of agent's kinematics in modulating observer's motor excitability. Here, we investigate whether explicit weight-related information, provided by written labels on the objects, modulate the excitability of the observer's motor system and how this modulation is affected when there is a conflict between label and object's weight. We measured TMS-evoked motor potentials (MEPs) from right hand intrinsic muscles, while subjects were observing an actor lifting objects of different weights, in some trials labeled (heavy/light) in congruent or incongruent way. Results confirmed a weight-related modulation of MEPs based on kinematic cues. Interestingly, any conflict between the labels and the actual weight (i.e., explicit versus implicit information), although never consciously noticed by the observer, deeply affected the mirroring of others' actions. Our findings stress the automatic involvement of the mirror-neuron system. Springer-Verlag, 2011 Action observation nationallicence Grip force nationallicence Mirror system nationallicence Transcranial magnetic stimulation nationallicence Senot Patrice D.S.B.T.A. Section of Human Physiology, University of Ferrara, Via Fossato di Mortara 17/19, 44100, Ferrara, Italy aut D'Ausilio Alessandro Department RBCS, The Italian Institute of Technology, Via Morego 30, Genoa, Italy aut Franca Michele D.S.B.T.A. Section of Human Physiology, University of Ferrara, Via Fossato di Mortara 17/19, 44100, Ferrara, Italy aut Caselli Luana D.S.B.T.A. Section of Human Physiology, University of Ferrara, Via Fossato di Mortara 17/19, 44100, Ferrara, Italy aut Craighero Laila D.S.B.T.A. Section of Human Physiology, University of Ferrara, Via Fossato di Mortara 17/19, 44100, Ferrara, Italy aut Fadiga Luciano D.S.B.T.A. Section of Human Physiology, University of Ferrara, Via Fossato di Mortara 17/19, 44100, Ferrara, Italy aut Experimental Brain Research Springer-Verlag 211/1(2011-05-01), 161-167 0014-4819 211:1<161 2011 211 221 https://doi.org/10.1007/s00221-011-2635-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00221-011-2635-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Senot Patrice D.S.B.T.A. Section of Human Physiology, University of Ferrara, Via Fossato di Mortara 17/19, 44100, Ferrara, Italy aut NATIONALLICENCE 700 1- D'Ausilio Alessandro Department RBCS, The Italian Institute of Technology, Via Morego 30, Genoa, Italy aut NATIONALLICENCE 700 1- Franca Michele D.S.B.T.A. Section of Human Physiology, University of Ferrara, Via Fossato di Mortara 17/19, 44100, Ferrara, Italy aut NATIONALLICENCE 700 1- Caselli Luana D.S.B.T.A. Section of Human Physiology, University of Ferrara, Via Fossato di Mortara 17/19, 44100, Ferrara, Italy aut NATIONALLICENCE 700 1- Craighero Laila D.S.B.T.A. Section of Human Physiology, University of Ferrara, Via Fossato di Mortara 17/19, 44100, Ferrara, Italy aut NATIONALLICENCE 700 1- Fadiga Luciano D.S.B.T.A. Section of Human Physiology, University of Ferrara, Via Fossato di Mortara 17/19, 44100, Ferrara, Italy aut NATIONALLICENCE 773 0- Experimental Brain Research Springer-Verlag 211/1(2011-05-01), 161-167 0014-4819 211:1<161 2011 211 221 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer