caa a22 4500 445352418 CHVBK 20180317142848.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s00221-011-2795-8 doi (NATIONALLICENCE)springer-10.1007/s00221-011-2795-8 Trunk sway in mildly disabled multiple sclerosis patients with and without balance impairment [Elektronische Daten] [Oliver Findling, Johann Sellner, Niklaus Meier, John Allum, Dominique Vibert, Carmen Lienert, Heinrich Mattle] Multiple sclerosis (MS) causes a broad range of neurological symptoms. Most common is poor balance control. However, knowledge of deficient balance control in mildly affected MS patients who are complaining of balance impairment but have normal clinical balance tests (CBT) is limited. This knowledge might provide insights into the normal and pathophysiological mechanisms underlying stance and gait. We analysed differences in trunk sway between mildly disabled MS patients with and without subjective balance impairment (SBI), all with normal CBT. The sway was measured for a battery of stance and gait balance tests (static and dynamic posturography) and compared to that of age- and sex-matched healthy subjects. Eight of 21 patients (38%) with an Expanded Disability Status Scale of 1.0-3.0 complained of SBI during daily activities. For standing on both legs with eyes closed on a normal and on a foam surface, patients in the no SBI group showed significant differences in the range of trunk roll (lateral) sway angle and velocity, compared to normal persons. Patients in the SBI group had significantly greater lateral sway than the no SBI group, and sway was also greater than normal in the pitch (anterior-posterior) direction. Sway for one-legged stance on foam was also greater in the SBI group compared to the no SBI and normal groups. We found a specific laterally directed impairment of balance in all patients, consistent with a deficit in proprioceptive processing, which was greater in the SBI group than in the no SBI group. This finding most likely explains the subjective symptoms of imbalance in patients with MS with normal CBT. Springer-Verlag, 2011 Multiple sclerosis nationallicence Posturography nationallicence Balance nationallicence Rehabilitation nationallicence Findling Oliver Department of Neurology, Inselspital, Bern University Hospital, Bern, Switzerland aut Sellner Johann Department of Neurology, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, München, Germany aut Meier Niklaus Department of Neurology, Inselspital, Bern University Hospital, Bern, Switzerland aut Allum John Department of Otorhinolaryngology, Basel University Hospital, Basel, Switzerland aut Vibert Dominique Department of Otorhinolaryngology-Head and Neck Surgery, Inselspital, Bern University Hospital, Bern, Switzerland aut Lienert Carmen Department of Neurology, Inselspital, Bern University Hospital, Bern, Switzerland aut Mattle Heinrich Department of Neurology, Inselspital, Bern University Hospital, Bern, Switzerland aut Experimental Brain Research Springer-Verlag 213/4(2011-09-01), 363-370 0014-4819 213:4<363 2011 213 221 https://doi.org/10.1007/s00221-011-2795-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00221-011-2795-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Findling Oliver Department of Neurology, Inselspital, Bern University Hospital, Bern, Switzerland aut NATIONALLICENCE 700 1- Sellner Johann Department of Neurology, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, München, Germany aut NATIONALLICENCE 700 1- Meier Niklaus Department of Neurology, Inselspital, Bern University Hospital, Bern, Switzerland aut NATIONALLICENCE 700 1- Allum John Department of Otorhinolaryngology, Basel University Hospital, Basel, Switzerland aut NATIONALLICENCE 700 1- Vibert Dominique Department of Otorhinolaryngology-Head and Neck Surgery, Inselspital, Bern University Hospital, Bern, Switzerland aut NATIONALLICENCE 700 1- Lienert Carmen Department of Neurology, Inselspital, Bern University Hospital, Bern, Switzerland aut NATIONALLICENCE 700 1- Mattle Heinrich Department of Neurology, Inselspital, Bern University Hospital, Bern, Switzerland aut NATIONALLICENCE 773 0- Experimental Brain Research Springer-Verlag 213/4(2011-09-01), 363-370 0014-4819 213:4<363 2011 213 221 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer