caa a22 4500 44535254X CHVBK 20180317142848.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00221-011-2902-x doi (NATIONALLICENCE)springer-10.1007/s00221-011-2902-x Cortical responses to the mirror box illusion: a high-resolution EEG study [Elektronische Daten] [Line Egsgaard, Laura Petrini, Giselle Christoffersen, Lars Arendt-Nielsen] The mirror box illusion has proven a helpful therapy in pathologies such as phantom limb pain, and although the effect has been suggested to be a result of the interaction between pain, vision, touch, and proprioception, the mechanisms are still unknown. Multichannel (124) brain responses were investigated in healthy men (N=11) and women (N=14) during the mirror box illusion. Tactile somatosensory evoked potentials were recorded from the right thumb during two control conditions and two illusions: (control 1) no mirror: looking at the physical right thumb during stimulation, (control 2) no mirror: looking at the physical left thumb during stimulation, (illusion 1) mirror: the illusion that both thumbs were stimulated, and (illusion 2) mirror: the illusion that none of the thumbs were stimulated. In men, a significant medial shift in the y coordinate of the N70 dipole in illusion 2 (P=0.021) was found when compared with illusion 1. No dipole shift was found for women. Additionally, men showed higher prevalence of P180 cingulate cortex activation during illusion 2 when compared with control 1 and 2 (P=0.002). During illusion 2, the degree of conformity with the statement "The hand in the mirror feels like my other hand” was negatively correlated with the N70 x coordinate for men and positively correlated with the N70 z coordinate for women. In conclusion, short-term cortical plasticity can be induced by a mismatch between visual input and location of tactile stimulation in men. The present study suggests that gender differences exist in the perception of the mirror box illusion. Springer-Verlag, 2011 Somatosensory evoked potentials nationallicence Mirror box illusion nationallicence Cortical plasticity nationallicence Gender differences nationallicence Visual illusion nationallicence Egsgaard Line Department of Health Science and Technology, Center for Sensory Motor Interaction, Faculty of Medicine, Aalborg University, Frederik Bajers Vej 7A, 9220, Aalborg East, Denmark aut Petrini Laura Department of Health Science and Technology, Center for Sensory Motor Interaction, Faculty of Medicine, Aalborg University, Frederik Bajers Vej 7A, 9220, Aalborg East, Denmark aut Christoffersen Giselle Department of Health Science and Technology, Center for Sensory Motor Interaction, Faculty of Medicine, Aalborg University, Frederik Bajers Vej 7A, 9220, Aalborg East, Denmark aut Arendt-Nielsen Lars Department of Health Science and Technology, Center for Sensory Motor Interaction, Faculty of Medicine, Aalborg University, Frederik Bajers Vej 7A, 9220, Aalborg East, Denmark aut Experimental Brain Research Springer-Verlag 215/3-4(2011-12-01), 345-357 0014-4819 215:3-4<345 2011 215 221 https://doi.org/10.1007/s00221-011-2902-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00221-011-2902-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Egsgaard Line Department of Health Science and Technology, Center for Sensory Motor Interaction, Faculty of Medicine, Aalborg University, Frederik Bajers Vej 7A, 9220, Aalborg East, Denmark aut NATIONALLICENCE 700 1- Petrini Laura Department of Health Science and Technology, Center for Sensory Motor Interaction, Faculty of Medicine, Aalborg University, Frederik Bajers Vej 7A, 9220, Aalborg East, Denmark aut NATIONALLICENCE 700 1- Christoffersen Giselle Department of Health Science and Technology, Center for Sensory Motor Interaction, Faculty of Medicine, Aalborg University, Frederik Bajers Vej 7A, 9220, Aalborg East, Denmark aut NATIONALLICENCE 700 1- Arendt-Nielsen Lars Department of Health Science and Technology, Center for Sensory Motor Interaction, Faculty of Medicine, Aalborg University, Frederik Bajers Vej 7A, 9220, Aalborg East, Denmark aut NATIONALLICENCE 773 0- Experimental Brain Research Springer-Verlag 215/3-4(2011-12-01), 345-357 0014-4819 215:3-4<345 2011 215 221 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer