caa a22 4500 445354062 CHVBK 20180317142854.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s00221-010-2450-9 doi (NATIONALLICENCE)springer-10.1007/s00221-010-2450-9 How the vestibular system modulates tactile perception in normal subjects: a behavioural and physiological study [Elektronische Daten] [Elisa Ferrè, Anna Sedda, Martina Gandola, Gabriella Bottini] Caloric vestibular stimulation (CVS) is a physiological technique demonstrated to transiently improve hemianaesthesia in right brain-damaged patients (Bottini et al. in Exp Brain Res 99(1):164-169, 1994, Nature 376:778-781, 1995, Neurology 65(8):1278-1283, 2005). Recent studies suggest that these effects are based on the anatomical overlapping between vestibular and tactile projections (Bottini et al. in Nature 376:778-781, 1995) in the human brain. However, much less is known about behavioural effects of this manipulation on normal subjects. We aimed to explore tactile perception during left ear CVS in normal subjects. We administered seventeen right-handed normal subjects with different types of tactile stimuli (above and below threshold) during left ear CVS. To further ensure standardized procedure, tactile stimulation was delivered through a tool-developed ad hoc for the experiment. The experiment was divided in 3 conditions: (1) Baseline, (2) PostCVS and (3) Delayed CVS. We found a main effect of stimulus type (F (2,32)=907.712; P=0.000) and condition (F (2,32)=55.505; P=0.000). Moreover, post hoc comparisons revealed that below threshold stimuli are most affected by CVS (t (16)=−11.213; P=0.000). Left ear CVS modulates tactile perception also in normal subjects. Moreover, this modulation seems to be selective for below threshold stimuli and not caused by attentive processes. A multisensory phenomenon is possibly the best explanation for this interaction between touch and vestibular systems, corroborated also by the anatomical evidence and by the previous knowledge about interaction with the environment. Springer-Verlag, 2010 Caloric vestibular stimulation nationallicence Touch imperception nationallicence Multisensory integration nationallicence Ferrè Elisa Department of Psychology, University of Pavia, Piazza Botta 6, 27100, Pavia, Italy aut Sedda Anna Department of Psychology, University of Pavia, Piazza Botta 6, 27100, Pavia, Italy aut Gandola Martina Department of Psychology, University of Milano Bicocca, Milan, Italy aut Bottini Gabriella Department of Psychology, University of Pavia, Piazza Botta 6, 27100, Pavia, Italy aut Experimental Brain Research Springer-Verlag 208/1(2011-01-01), 29-38 0014-4819 208:1<29 2011 208 221 https://doi.org/10.1007/s00221-010-2450-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00221-010-2450-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ferrè Elisa Department of Psychology, University of Pavia, Piazza Botta 6, 27100, Pavia, Italy aut NATIONALLICENCE 700 1- Sedda Anna Department of Psychology, University of Pavia, Piazza Botta 6, 27100, Pavia, Italy aut NATIONALLICENCE 700 1- Gandola Martina Department of Psychology, University of Milano Bicocca, Milan, Italy aut NATIONALLICENCE 700 1- Bottini Gabriella Department of Psychology, University of Pavia, Piazza Botta 6, 27100, Pavia, Italy aut NATIONALLICENCE 773 0- Experimental Brain Research Springer-Verlag 208/1(2011-01-01), 29-38 0014-4819 208:1<29 2011 208 221 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer