caa a22 4500 445354496 CHVBK 20180317142855.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s00221-010-2478-x doi (NATIONALLICENCE)springer-10.1007/s00221-010-2478-x Alterations in human motor cortex during dual motor task by transcranial magnetic stimulation study [Elektronische Daten] [Kazumasa Uehara, Toshio Higashi, Shigeo Tanabe, Kenichi Sugawara] The aim of this study was to determine how and whether changes in the primary motor cortex (M1) are affected by dual motor task. We further investigated how dual motor task is dependent on task properties measured using transcranial magnetic stimulation (TMS). TMS delivered to left M1 during the dual motor task and motor-evoked potential (MEP) were simultaneously evoked in the right FDI, thenar, FCR and ECR muscles. In experiment 1, subjects were asked to simultaneously walk on a treadmill and perform finger prehension. The gait conditions were employed 30, 50 and 80% of maximum walking speed (gait 30%, gait 50% and gait 80%). Conditions for finger prehension while following the visual tracking task varied with force outputs of 5 and 25% of maximum voluntary contraction (MVC). In experiment 2, the subjects were asked to perform optimal walking synchronized with the finger prehension task with an optimal walking rhythm (2-Hz dual motor task), as well as optimal walking desynchronized with the finger prehension task (0.7-Hz dual motor task). In experiment 1, MEPs were markedly decreased under the gait 50% condition compared with those under the gait 30 and 80% conditions at 5% MVC. In experiment 2, MEPs were markedly decreased with the 2-Hz dual motor task compared with those with the 0.7-Hz dual motor task. Our results suggest that the excitability changes in M1 during the dual motor task were dependent on changes in the gait speed, precision of prehension task and temporal movement. Springer-Verlag, 2010 Dual motor task nationallicence Motor-evoked potential (MEP) nationallicence Transcranial magnetic stimulation (TMS) nationallicence Primary motor cortex (M1) nationallicence Uehara Kazumasa Rehabilitation Science, Division of Health & Social Work, Graduate School of Health & Social Work Sciences, Kanagawa University of Human Services, 1-10-1 Heisei-cho, 238-8522, Yokosuka, Kanagawa, Japan aut Higashi Toshio Faculty of Health & Social Work, School of Rehabilitation, Kanagawa University of Human Services, 1-10-1 Heisei-cho, 238-8522, Yokosuka, Kanagawa, Japan aut Tanabe Shigeo Faculty of Rehabilitation, School of Health Sciences, Fujita Health University, 1-98 Dengakugakubo Kutsukake-cho, 470-1192, Toyoake, Aichi, Japan aut Sugawara Kenichi Faculty of Health & Social Work, School of Rehabilitation, Kanagawa University of Human Services, 1-10-1 Heisei-cho, 238-8522, Yokosuka, Kanagawa, Japan aut Experimental Brain Research Springer-Verlag 208/2(2011-01-01), 277-286 0014-4819 208:2<277 2011 208 221 https://doi.org/10.1007/s00221-010-2478-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00221-010-2478-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Uehara Kazumasa Rehabilitation Science, Division of Health & Social Work, Graduate School of Health & Social Work Sciences, Kanagawa University of Human Services, 1-10-1 Heisei-cho, 238-8522, Yokosuka, Kanagawa, Japan aut NATIONALLICENCE 700 1- Higashi Toshio Faculty of Health & Social Work, School of Rehabilitation, Kanagawa University of Human Services, 1-10-1 Heisei-cho, 238-8522, Yokosuka, Kanagawa, Japan aut NATIONALLICENCE 700 1- Tanabe Shigeo Faculty of Rehabilitation, School of Health Sciences, Fujita Health University, 1-98 Dengakugakubo Kutsukake-cho, 470-1192, Toyoake, Aichi, Japan aut NATIONALLICENCE 700 1- Sugawara Kenichi Faculty of Health & Social Work, School of Rehabilitation, Kanagawa University of Human Services, 1-10-1 Heisei-cho, 238-8522, Yokosuka, Kanagawa, Japan aut NATIONALLICENCE 773 0- Experimental Brain Research Springer-Verlag 208/2(2011-01-01), 277-286 0014-4819 208:2<277 2011 208 221 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer