caa a22 4500 445354577 CHVBK 20180317142855.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s00221-010-2481-2 doi (NATIONALLICENCE)springer-10.1007/s00221-010-2481-2 What is ‘anti' about anti-reaches? Reference frames selectively affect reaction times and endpoint variability [Elektronische Daten] [Stephanie Westendorff, Alexander Gail] Reach movement planning involves the representation of spatial target information in different reference frames. Neurons at parietal and premotor stages of the cortical sensorimotor system represent target information in eye- or hand-centered reference frames, respectively. How the different neuronal representations affect behavioral parameters of motor planning and control, i.e. which stage of neural representation is relevant for which aspect of behavior, is not obvious from the physiology. Here, we test with a behavioral experiment if different kinematic movement parameters are affected to a different degree by either an eye- or hand-reference frame. We used a generalized anti-reach task to test the influence of stimulus-response compatibility (SRC) in eye- and hand-reference frames on reach reaction times, movement times, and endpoint variability. While in a standard anti-reach task, the SRC is identical in the eye- and hand-reference frames, we could separate SRC for the two reference frames. We found that reaction times were influenced by the SRC in eye- and hand-reference frame. In contrast, movement times were only influenced by the SRC in hand-reference frame, and endpoint variability was only influenced by the SRC in eye-reference frame. Since movement time and endpoint variability are the result of planning and control processes, while reaction times are consequences of only the planning process, we suggest that SRC effects on reaction times are highly suited to investigate reference frames of movement planning, and that eye- and hand-reference frames have distinct effects on different phases of motor action and different kinematic movement parameters. The Author(s), 2010 Reach planning nationallicence Stimulus-response compatibility nationallicence Reference frames nationallicence Sensorimotor transformation nationallicence Eye-hand coordination nationallicence Westendorff Stephanie Bernstein Center for Computational Neuroscience Göttingen, German Primate Center, Kellnerweg 4, 37077, Göttingen, Germany aut Gail Alexander Bernstein Center for Computational Neuroscience Göttingen, German Primate Center, Kellnerweg 4, 37077, Göttingen, Germany aut Experimental Brain Research Springer-Verlag 208/2(2011-01-01), 287-296 0014-4819 208:2<287 2011 208 221 https://doi.org/10.1007/s00221-010-2481-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00221-010-2481-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Westendorff Stephanie Bernstein Center for Computational Neuroscience Göttingen, German Primate Center, Kellnerweg 4, 37077, Göttingen, Germany aut NATIONALLICENCE 700 1- Gail Alexander Bernstein Center for Computational Neuroscience Göttingen, German Primate Center, Kellnerweg 4, 37077, Göttingen, Germany aut NATIONALLICENCE 773 0- Experimental Brain Research Springer-Verlag 208/2(2011-01-01), 287-296 0014-4819 208:2<287 2011 208 221 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer