caa a22 4500 445354585 CHVBK 20180317142855.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s00221-010-2470-5 doi (NATIONALLICENCE)springer-10.1007/s00221-010-2470-5 Premovement brain activity in a bimanual load-lifting task [Elektronische Daten] [Tommy Ng, Paul Sowman, Jon Brock, Blake Johnson] Even the simplest volitional movements must be precisely coordinated with anticipatory postural adjustments. Little is currently known about the neural networks that coordinate these adjustments in healthy adults. We measured brain activity prior to movement during a bimanual load-lifting task, designed to elicit anticipatory adjustments in a restricted and well-defined set of musculature in the arm. Electroencephalography and magnetoencephalography brain measurements were obtained from eleven participants while they performed a bimanual load-lifting task that required precise inter-limb coordination. Anticipatory biceps brachii inhibition in the loaded arm was associated with a robust desynchronization of the beta rhythm. Beamforming analyses localized beta band responses to the parietal lobules, pre- and post-central gyri, middle and medial frontal gyri, basal ganglia and thalamus. The current study shows that premovement brain activity in a bimanual load-lifting task can be imaged with magnetoencephalography. Future experiments will partition out brain activity associated with anticipatory postural adjustments and volitional movements. The experimental paradigm will also be useful in the study of motor function in patients with developmental or degenerative disorders. Springer-Verlag, 2010 Anticipatory postural adjustments nationallicence Beamforming nationallicence Bimanual load-lifting task nationallicence Event-related desynchronization nationallicence Magnetoencephalography nationallicence Motor coordination nationallicence Ng Tommy Macquarie Centre for Cognitive Science, Macquarie University, Sydney, Australia aut Sowman Paul Macquarie Centre for Cognitive Science, Macquarie University, Sydney, Australia aut Brock Jon Macquarie Centre for Cognitive Science, Macquarie University, Sydney, Australia aut Johnson Blake Macquarie Centre for Cognitive Science, Macquarie University, Sydney, Australia aut Experimental Brain Research Springer-Verlag 208/2(2011-01-01), 189-201 0014-4819 208:2<189 2011 208 221 https://doi.org/10.1007/s00221-010-2470-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00221-010-2470-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ng Tommy Macquarie Centre for Cognitive Science, Macquarie University, Sydney, Australia aut NATIONALLICENCE 700 1- Sowman Paul Macquarie Centre for Cognitive Science, Macquarie University, Sydney, Australia aut NATIONALLICENCE 700 1- Brock Jon Macquarie Centre for Cognitive Science, Macquarie University, Sydney, Australia aut NATIONALLICENCE 700 1- Johnson Blake Macquarie Centre for Cognitive Science, Macquarie University, Sydney, Australia aut NATIONALLICENCE 773 0- Experimental Brain Research Springer-Verlag 208/2(2011-01-01), 189-201 0014-4819 208:2<189 2011 208 221 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer