caa a22 4500 445355409 CHVBK 20180317142858.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s10072-010-0426-y doi (NATIONALLICENCE)springer-10.1007/s10072-010-0426-y Accuracy of pre-surgical fMRI confirmed by subsequent crossed aphasia [Elektronische Daten] [Paolo Vitali, Nina Dronkers, Alexander Pincherle, Anna Giovagnoli, Carlo Marras, Ludovico D'Incerti, Francesco Ghielmetti, Roberto Spreafico, Flavio Villani] Atypical patterns of language activation in functional MRI (fMRI) are not unusual, particularly in patients with severe epilepsy. Still, the functional significance of these activations is under debate. We describe a case of a right-handed patient affected by drug-refractory right temporal lobe epilepsy in whom pre-surgical fMRI showed bilateral language activations, greater in the right hemisphere (RH). After surgery, a right subdural hematoma caused epileptic status and severe aphasia. This post-surgical complication of a crossed aphasia confirmed the prior fMRI findings of RH language thus stressing the value of pre-surgical fMRI evaluations, even when surgery is planned in the RH of a right-handed patient. Springer-Verlag, 2010 Language nationallicence Hemispheric dominance nationallicence Crossed aphasia nationallicence Temporal lobe epilepsy nationallicence Functional MRI nationallicence Vitali Paolo Division of Neuroradiology, Department of Diagnostics and Applied Technology, Foundation IRCCS National Neurological Institute "C. Besta”, Milan, Italy aut Dronkers Nina Center for Aphasia and Related Disorders, VA Northern California Health Care System, Mather, USA aut Pincherle Alexander Division of Clinical Epileptology and Experimental Neurophysiology, Department of Diagnostics and Applied Technology, Foundation IRCCS Neurological Institute "C. Besta”, Milan, Italy aut Giovagnoli Anna Laboratory of Neuropsychology, Department of Clinical Neurosciences, Foundation IRCCS Neurological Institute "C. Besta”, Milan, Italy aut Marras Carlo Division of Neurosurgery III, Department of Neurosurgery, Foundation IRCCS Neurological Institute "C. Besta”, Milan, Italy aut D'Incerti Ludovico Division of Neuroradiology, Department of Diagnostics and Applied Technology, Foundation IRCCS National Neurological Institute "C. Besta”, Milan, Italy aut Ghielmetti Francesco Division of Neuroradiology, Department of Diagnostics and Applied Technology, Foundation IRCCS National Neurological Institute "C. Besta”, Milan, Italy aut Spreafico Roberto Division of Clinical Epileptology and Experimental Neurophysiology, Department of Diagnostics and Applied Technology, Foundation IRCCS Neurological Institute "C. Besta”, Milan, Italy aut Villani Flavio Division of Clinical Epileptology and Experimental Neurophysiology, Department of Diagnostics and Applied Technology, Foundation IRCCS Neurological Institute "C. Besta”, Milan, Italy aut Neurological Sciences Springer Milan 32/1(2011-02-01), 175-180 1590-1874 32:1<175 2011 32 10072 https://doi.org/10.1007/s10072-010-0426-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-010-0426-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vitali Paolo Division of Neuroradiology, Department of Diagnostics and Applied Technology, Foundation IRCCS National Neurological Institute "C. Besta”, Milan, Italy aut NATIONALLICENCE 700 1- Dronkers Nina Center for Aphasia and Related Disorders, VA Northern California Health Care System, Mather, USA aut NATIONALLICENCE 700 1- Pincherle Alexander Division of Clinical Epileptology and Experimental Neurophysiology, Department of Diagnostics and Applied Technology, Foundation IRCCS Neurological Institute "C. Besta”, Milan, Italy aut NATIONALLICENCE 700 1- Giovagnoli Anna Laboratory of Neuropsychology, Department of Clinical Neurosciences, Foundation IRCCS Neurological Institute "C. Besta”, Milan, Italy aut NATIONALLICENCE 700 1- Marras Carlo Division of Neurosurgery III, Department of Neurosurgery, Foundation IRCCS Neurological Institute "C. Besta”, Milan, Italy aut NATIONALLICENCE 700 1- D'Incerti Ludovico Division of Neuroradiology, Department of Diagnostics and Applied Technology, Foundation IRCCS National Neurological Institute "C. Besta”, Milan, Italy aut NATIONALLICENCE 700 1- Ghielmetti Francesco Division of Neuroradiology, Department of Diagnostics and Applied Technology, Foundation IRCCS National Neurological Institute "C. Besta”, Milan, Italy aut NATIONALLICENCE 700 1- Spreafico Roberto Division of Clinical Epileptology and Experimental Neurophysiology, Department of Diagnostics and Applied Technology, Foundation IRCCS Neurological Institute "C. Besta”, Milan, Italy aut NATIONALLICENCE 700 1- Villani Flavio Division of Clinical Epileptology and Experimental Neurophysiology, Department of Diagnostics and Applied Technology, Foundation IRCCS Neurological Institute "C. Besta”, Milan, Italy aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/1(2011-02-01), 175-180 1590-1874 32:1<175 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer