caa a22 4500 445355476 CHVBK 20180317142858.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s10072-010-0457-4 doi (NATIONALLICENCE)springer-10.1007/s10072-010-0457-4 The usefulness of albumin-adjusted ischemia-modified albumin index as early detecting marker for ischemic stroke [Elektronische Daten] [Jung Ahn, Sang Choi, Wee Lee, Yoon Jung] This study was conducted to investigate whether albumin-adjusted ischemia-modified albumin index (IMA index) is more sensitive and accurate than ischemia-modified albumin (IMA) as early detection marker of ischemic stroke, and to compare IMA and IMA index in progression and non-progression of ischemic stroke. This case-control study was done at an emergency medical center of a university hospital. 52 patients with neurological symptoms were enrolled (28 Ischemic Stroke Group and 24 Non-Stroke Group). In the ROC analysis of IMA index to diagnose stroke, area under the curve (AUC) was 0.990 (cutoff value 91.4; 95% CI: 0.970-1.000; sensitivity: 95.8%; specificity: 96.4%). The AUC for IMA value was 0.928 (cutoff value 98U/ml; 95% CI: 0.857-0.999; sensitivity: 87.5%; specificity: 89.3%). The difference between progression (n=12) and non-progression group (n=16) in IMA and IMA index were statistically insignificant (p>0.01). IMA index was more sensitive than conventional IMA value as diagnostic biomarker of stroke, however, arguable as a predictive biomarker for progression of ischemic stroke. Springer-Verlag, 2010 Ischemia nationallicence Ischemia-modified albumin nationallicence Ischemic stroke nationallicence Serum albumin-adjusted IMA index nationallicence Ahn Jung Emergency Department, Ajou University School of Medicine, Woncheon-dong, Yeongtong-gu, 443-721, Suwon, Republic of Korea aut Choi Sang Emergency Department, Ajou University School of Medicine, Woncheon-dong, Yeongtong-gu, 443-721, Suwon, Republic of Korea aut Lee Wee Department of Clinicopathology, Ajou University School of Medicine, Woncheon-dong, Yeongtong-gu, 443-721, Suwon, Republic of Korea aut Jung Yoon Emergency Department, Ajou University School of Medicine, Woncheon-dong, Yeongtong-gu, 443-721, Suwon, Republic of Korea aut Neurological Sciences Springer Milan 32/1(2011-02-01), 133-138 1590-1874 32:1<133 2011 32 10072 https://doi.org/10.1007/s10072-010-0457-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-010-0457-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ahn Jung Emergency Department, Ajou University School of Medicine, Woncheon-dong, Yeongtong-gu, 443-721, Suwon, Republic of Korea aut NATIONALLICENCE 700 1- Choi Sang Emergency Department, Ajou University School of Medicine, Woncheon-dong, Yeongtong-gu, 443-721, Suwon, Republic of Korea aut NATIONALLICENCE 700 1- Lee Wee Department of Clinicopathology, Ajou University School of Medicine, Woncheon-dong, Yeongtong-gu, 443-721, Suwon, Republic of Korea aut NATIONALLICENCE 700 1- Jung Yoon Emergency Department, Ajou University School of Medicine, Woncheon-dong, Yeongtong-gu, 443-721, Suwon, Republic of Korea aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/1(2011-02-01), 133-138 1590-1874 32:1<133 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer