caa a22 4500 445355514 CHVBK 20180317142858.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s10072-010-0407-1 doi (NATIONALLICENCE)springer-10.1007/s10072-010-0407-1 The relevance of early TCD monitoring in the intensive care units for the confirming of brain death diagnosis [Elektronische Daten] [Marinella Marinoni, Fabiana Alari, Veronica Mastronardi, Adriano Peris, Paola Innocenti] Brain death (BD) diagnosis is the clinical assessment of the irreversible loss of function of the entire brain, including the brainstem. Transcranial Doppler (TCD) examination is used in several countries as a confirmatory test to assess cerebral circulatory arrest (CCA). A total of 1,400 TCD examinations were performed in 623 patients (pts) admitted to intensive care units (ICUs) of our hospital during the last 6years. Oscillating flow, systolic spikes and the absence of any TCD signal were considered as diagnostic patterns of irreversible CCA. TCD patterns of CCA were detected in 56 pts. In 25 pts, deeply sedated with barbiturate therapy, TCD was employed as confirmatory test for BD diagnosis and 14 of them could become organ and/or tissue donors. TCD is a safe and inexpensive tool that can be performed at the bedside, and it allows to shorten the diagnostic process of BD, which is the prerequisite for organ donation. Springer-Verlag, 2010 Transcranial Doppler nationallicence Brain death nationallicence Intensive care units nationallicence Barbiturate coma nationallicence Marinoni Marinella Department of Neurological and Psychiatrics Sciences, University of Florence, Viale Morgagni, 85, 50134, Florence, Italy aut Alari Fabiana Department of Neurological and Psychiatrics Sciences, University of Florence, Viale Morgagni, 85, 50134, Florence, Italy aut Mastronardi Veronica Department of Neurological and Psychiatrics Sciences, University of Florence, Viale Morgagni, 85, 50134, Florence, Italy aut Peris Adriano Emergency Department, University of Florence, Florence, Italy aut Innocenti Paola Department of Neurological and Psychiatrics Sciences, University of Florence, Viale Morgagni, 85, 50134, Florence, Italy aut Neurological Sciences Springer Milan 32/1(2011-02-01), 73-77 1590-1874 32:1<73 2011 32 10072 https://doi.org/10.1007/s10072-010-0407-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-010-0407-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Marinoni Marinella Department of Neurological and Psychiatrics Sciences, University of Florence, Viale Morgagni, 85, 50134, Florence, Italy aut NATIONALLICENCE 700 1- Alari Fabiana Department of Neurological and Psychiatrics Sciences, University of Florence, Viale Morgagni, 85, 50134, Florence, Italy aut NATIONALLICENCE 700 1- Mastronardi Veronica Department of Neurological and Psychiatrics Sciences, University of Florence, Viale Morgagni, 85, 50134, Florence, Italy aut NATIONALLICENCE 700 1- Peris Adriano Emergency Department, University of Florence, Florence, Italy aut NATIONALLICENCE 700 1- Innocenti Paola Department of Neurological and Psychiatrics Sciences, University of Florence, Viale Morgagni, 85, 50134, Florence, Italy aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/1(2011-02-01), 73-77 1590-1874 32:1<73 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer