caa a22 4500 445355603 CHVBK 20180317142859.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10072-011-0606-4 doi (NATIONALLICENCE)springer-10.1007/s10072-011-0606-4 Synaptic organization of the rat thalamus: a quantitative study [Elektronische Daten] [Safiye Çavdar, Hüsniye Hacıoğlu, Serap Şirvancı, Elif Keskinöz, Filiz Onat] First-order thalamic nuclei receive driving afferents from ascending pathways and transmit processed information to the cortex. Higher-order thalamic nuclei receive driver messages from layer 5 of cortex and transmit information from one cortical area to the other. The different types of axon terminals RL (round vesicles, large terminals), RS (round vesicles, small terminals) and F (flattened vesicles) and their synaptic junctions have been here compared in three first-order (ventrobasal, lateral geniculate and anteroventral) and three higher-order (posterior, lateral posterior and mediodorsal) thalamic nuclei of the rat. In the present study, the higher-order relays differ from first-order relays as in the cat, in having fewer driver terminals (RL) and synapses than do the first-order relays. However, the F terminals showed opposite ratios in the first versus higher-order thalamic nuclei. The majority of the terminals in all thalamic nuclei studied were RS terminals. The area measurements of the three types of terminals and synaptic lengths showed no significant differences between first and higher-order nuclei. The driver inputs represent the minority and the modulatory inputs represent the majority of the terminals and synapses in all thalamic nuclei. In conclusion, there is a relative paucity of driver inputs, whereas modulatory inputs establish more numerous synapses to achieve finer modulation. Springer-Verlag, 2011 GABA immunostaining nationallicence Electron microscopy nationallicence Drivers nationallicence Modulators nationallicence Çavdar Safiye Department of Anatomy, School of Medicine, University of Marmara, Haydarpaşa, 34668, Istanbul, Turkey aut Hacıoğlu Hüsniye Department of Anatomy, School of Medicine, University of Marmara, Haydarpaşa, 34668, Istanbul, Turkey aut Şirvancı Serap Department of Histology and Embryology, School of Medicine, University of Marmara, Haydarpaşa, 34668, Istanbul, Turkey aut Keskinöz Elif Department of Anatomy, School of Medicine, University of Marmara, Haydarpaşa, 34668, Istanbul, Turkey aut Onat Filiz Department of Pharmacology and Clinical Pharmacology, School of Medicine, University of Marmara, Haydarpaşa, 34668, Istanbul, Turkey aut Neurological Sciences Springer Milan 32/6(2011-12-01), 1047-1056 1590-1874 32:6<1047 2011 32 10072 https://doi.org/10.1007/s10072-011-0606-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-011-0606-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Çavdar Safiye Department of Anatomy, School of Medicine, University of Marmara, Haydarpaşa, 34668, Istanbul, Turkey aut NATIONALLICENCE 700 1- Hacıoğlu Hüsniye Department of Anatomy, School of Medicine, University of Marmara, Haydarpaşa, 34668, Istanbul, Turkey aut NATIONALLICENCE 700 1- Şirvancı Serap Department of Histology and Embryology, School of Medicine, University of Marmara, Haydarpaşa, 34668, Istanbul, Turkey aut NATIONALLICENCE 700 1- Keskinöz Elif Department of Anatomy, School of Medicine, University of Marmara, Haydarpaşa, 34668, Istanbul, Turkey aut NATIONALLICENCE 700 1- Onat Filiz Department of Pharmacology and Clinical Pharmacology, School of Medicine, University of Marmara, Haydarpaşa, 34668, Istanbul, Turkey aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/6(2011-12-01), 1047-1056 1590-1874 32:6<1047 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer