caa a22 4500 445355808 CHVBK 20180317142859.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10072-010-0442-y doi (NATIONALLICENCE)springer-10.1007/s10072-010-0442-y Epilepsia partialis continua in children with fulminant subacute sclerosing panencephalitis [Elektronische Daten] [Ruzica Kravljanac, Nebojsa Jovic, Milena Djuric, Ljubica Nikolic] Various inflammatory diseases of central nervous system, including subacute sclerosing panencephalitis, could cause epilepsia partialis continua. Two boys with epilepsia partialis continua with onset in terminal phase of atypical subacute sclerosing panencephalitis have been reported. Children were not vaccinated against measles, and the second case had history of measles at an early age. In both cases, the onset of subacute sclerosing panencephalitis was characterized by altered behavior and cognitive decline with very fast mental and neurological deterioration. One boy was suffering from complex partial seizures and myoclonic jerks synchronous with periodic electroencephalographic pattern. Diagnosis was proved by increased titers of antimeasles antibodies in both serum and cerebrospinal fluid. In terminal phase of the disease, epilepsia partialis continua of localized group of the muscles was diagnosed, with good response to intravenous infusion of midazolam. Surface electroencephalographic recordings during epilepsia partialis continua did not show the epileptic discharges. During the terminal phase of the disease, no other type of seizures and movement disorders were recognized, except epilepsia partialis continua. In spite of the treatment, period from the onset of disease to death lasted less than 3months, suggesting very fulminant course of subacute sclerosing panencephalitis. Springer-Verlag, 2010 Epilepsia partialis continua nationallicence Fulminant SSPE nationallicence Kravljanac Ruzica Institute for Mother and Child Health, University of Belgrade, 6-8 Radoje Dakic Street, 11070, Belgrade, Serbia aut Jovic Nebojsa Clinic for Neurology and Psychiatry for Children and Youth, University of Belgrade, 6 Dr Subotic Street, 11000, Belgrade, Serbia aut Djuric Milena Institute for Mother and Child Health, University of Belgrade, 6-8 Radoje Dakic Street, 11070, Belgrade, Serbia aut Nikolic Ljubica Institute for Mother and Child Health, University of Belgrade, 6-8 Radoje Dakic Street, 11070, Belgrade, Serbia aut Neurological Sciences Springer Milan 32/6(2011-12-01), 1007-1012 1590-1874 32:6<1007 2011 32 10072 https://doi.org/10.1007/s10072-010-0442-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-010-0442-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kravljanac Ruzica Institute for Mother and Child Health, University of Belgrade, 6-8 Radoje Dakic Street, 11070, Belgrade, Serbia aut NATIONALLICENCE 700 1- Jovic Nebojsa Clinic for Neurology and Psychiatry for Children and Youth, University of Belgrade, 6 Dr Subotic Street, 11000, Belgrade, Serbia aut NATIONALLICENCE 700 1- Djuric Milena Institute for Mother and Child Health, University of Belgrade, 6-8 Radoje Dakic Street, 11070, Belgrade, Serbia aut NATIONALLICENCE 700 1- Nikolic Ljubica Institute for Mother and Child Health, University of Belgrade, 6-8 Radoje Dakic Street, 11070, Belgrade, Serbia aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/6(2011-12-01), 1007-1012 1590-1874 32:6<1007 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer