caa a22 4500 445355832 CHVBK 20180317142859.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10072-011-0629-x doi (NATIONALLICENCE)springer-10.1007/s10072-011-0629-x Epilepsy in coeliac disease: not just a matter of calcifications [Elektronische Daten] [Laura Licchetta, Francesca Bisulli, Lidia Di Vito, Chiara La Morgia, Ilaria Naldi, Umberto Volta, Paolo Tinuper] The clinical spectrum of epilepsy related to celiac disease (CD) ranges from benign syndromes to intractable epilepsy with evolution to a severe encephalopathy, including progressive myoclonic epilepsy (PME). A more specific syndrome characterised by the association of CD, epilepsy, and occipital calcifications (CEC) has also been reported. This study describes the clinical, neuroradiological and neurophysiological features of eight consecutive epileptic patients with a diagnosis of CD confirmed by laboratory tests and duodenal biopsy, referring to our Epilepsy Centre. Despite its small size, this series reflects the broad spectrum of the association between the two diseases, since it includes four cases of CEC and a more heterogeneous group of patients without cerebral calcifications comprising one case of limbic encephalitis and a case of PME. Our cohort suggests that more complex pathogenic mechanisms may be involved in the association between epilepsy and CD, and that CD should be included in the screening for PME etiology. Our data also confirm the major involvement of the occipital lobe, and minimise both the importance of calcifications in epileptogenesis and folic acid deficit in the development of calcifications. Springer-Verlag, 2011 Coeliac disease nationallicence Cerebral calcifications nationallicence Progressive myoclonic epilepsies nationallicence Licchetta Laura Department of Neurological Sciences, University of Bologna, via Ugo Foscolo 7, 40123, Bologna, Italy aut Bisulli Francesca Department of Neurological Sciences, University of Bologna, via Ugo Foscolo 7, 40123, Bologna, Italy aut Di Vito Lidia Department of Neurological Sciences, University of Bologna, via Ugo Foscolo 7, 40123, Bologna, Italy aut La Morgia Chiara Department of Neurological Sciences, University of Bologna, via Ugo Foscolo 7, 40123, Bologna, Italy aut Naldi Ilaria Department of Neurological Sciences, University of Bologna, via Ugo Foscolo 7, 40123, Bologna, Italy aut Volta Umberto Department of Internal Medicine Cardioangiology, Hepatology, Policlinic S. Orsola-Malpighi, University of Bologna, Bologna, Italy aut Tinuper Paolo Department of Neurological Sciences, University of Bologna, via Ugo Foscolo 7, 40123, Bologna, Italy aut Neurological Sciences Springer Milan 32/6(2011-12-01), 1069-1074 1590-1874 32:6<1069 2011 32 10072 https://doi.org/10.1007/s10072-011-0629-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-011-0629-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Licchetta Laura Department of Neurological Sciences, University of Bologna, via Ugo Foscolo 7, 40123, Bologna, Italy aut NATIONALLICENCE 700 1- Bisulli Francesca Department of Neurological Sciences, University of Bologna, via Ugo Foscolo 7, 40123, Bologna, Italy aut NATIONALLICENCE 700 1- Di Vito Lidia Department of Neurological Sciences, University of Bologna, via Ugo Foscolo 7, 40123, Bologna, Italy aut NATIONALLICENCE 700 1- La Morgia Chiara Department of Neurological Sciences, University of Bologna, via Ugo Foscolo 7, 40123, Bologna, Italy aut NATIONALLICENCE 700 1- Naldi Ilaria Department of Neurological Sciences, University of Bologna, via Ugo Foscolo 7, 40123, Bologna, Italy aut NATIONALLICENCE 700 1- Volta Umberto Department of Internal Medicine Cardioangiology, Hepatology, Policlinic S. Orsola-Malpighi, University of Bologna, Bologna, Italy aut NATIONALLICENCE 700 1- Tinuper Paolo Department of Neurological Sciences, University of Bologna, via Ugo Foscolo 7, 40123, Bologna, Italy aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/6(2011-12-01), 1069-1074 1590-1874 32:6<1069 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer