caa a22 4500 445356057 CHVBK 20180317142900.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s10072-011-0571-y doi (NATIONALLICENCE)springer-10.1007/s10072-011-0571-y Cerebral microbleeds and quality of life in acute ischemic stroke [Elektronische Daten] [W. Tang, Y. Chen, J. Lu, A. Ahuja, W. Chu, V. Mok, G. Ungvari, Y. Xiang, K. Wong] This study evaluated the impact of cerebral microbleeds (CMBs) on the health-related quality of life (HRQoL) in 458 Chinese patients with first or recurrent acute ischemic stroke. HRQoL was assessed with the Short Form-36 (SF-36). Univariate analysis showed the presence of lobar CMBs to be negatively correlated with patients' physical functioning (PF; p<0.01), social function (SF; p<0.01), and role-emotional (RE; p<0.05) scores. Subsequent linear regression analysis revealed lobar CMBs to be independently associated with the PF and SF scores (p<0.05). The limitations of this study include the exclusion of patients with more severe stroke, the lack of longitudinal assessments, the use of a generic rather than stroke-specific HRQoL scale, and the less than optimal sensitivity of the CMB measurement. The study findings suggest that CMBs have a significant impact on the HRQoL of stroke survivors. Springer-Verlag, 2011 Quality of life nationallicence Stroke nationallicence Microbleeds nationallicence Tang W. Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China aut Chen Y. Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China aut Lu J. Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China aut Ahuja A. Department of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Hong Kong SAR, China aut Chu W. Department of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Hong Kong SAR, China aut Mok V. Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China aut Ungvari G. The University of Notre Dame Australia/Marian Centre, Perth, Australia aut Xiang Y. Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China aut Wong K. Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China aut Neurological Sciences Springer Milan 32/3(2011-06-01), 449-454 1590-1874 32:3<449 2011 32 10072 https://doi.org/10.1007/s10072-011-0571-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-011-0571-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tang W. Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China aut NATIONALLICENCE 700 1- Chen Y. Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China aut NATIONALLICENCE 700 1- Lu J. Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China aut NATIONALLICENCE 700 1- Ahuja A. Department of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Hong Kong SAR, China aut NATIONALLICENCE 700 1- Chu W. Department of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Hong Kong SAR, China aut NATIONALLICENCE 700 1- Mok V. Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China aut NATIONALLICENCE 700 1- Ungvari G. The University of Notre Dame Australia/Marian Centre, Perth, Australia aut NATIONALLICENCE 700 1- Xiang Y. Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China aut NATIONALLICENCE 700 1- Wong K. Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/3(2011-06-01), 449-454 1590-1874 32:3<449 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer