caa a22 4500 445356316 CHVBK 20180317142901.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s10072-011-0507-6 doi (NATIONALLICENCE)springer-10.1007/s10072-011-0507-6 Cerebral ischemia in young patients (under 45 years of age): clinical and neuroradiological follow-up [Elektronische Daten] [Rosalba Patella, Alessandra Spalloni, Marco Ferrari, Sara La Starza, Alessandro Bozzao, Maurizia Rasura] Ischemic stroke in young patients is a relatively rare event. Few studies have examined the long-term prognosis. The aim of this study was to evaluate the long-term outcome to identify clinical, laboratory and radiologic patterns as possible predictors for mortality, recurrence and functional recovery. We prospectively evaluated 94 patients (42 males and 52 females, aged 14-45years, mean age 35.5years, SD 8.4) admitted to our Neurological Department, for first acute ischemic stroke. A 48-month follow-up was performed. The patients were classified according to TOAST and Baltimore classification and Bamford criteria. The severity of the neurological deficit on admission was assessed using the NIHSS. The follow-up included a clinical visit, the modified Ranking scale (mRs) score, Barthel index (BI), and magnetic resonance imaging and intra-extracranial vessel Angio MRI. A good functional outcome (mRS 0-1) was found in 74 patients and unfavourable outcome (mRS 2-6) in 20 patients. 16 patients had a recurrent cerebral ischemic event: 5 patients had stroke and 11 patients had TIA. The average incidence annual rate of recurrence was 4.5% and a mortality rate was of 1.06%. Our study does not demonstrate any predictive factor related to clinical outcome. The relevant data of neuroradiological follow-up is the presence of clinically silent lesions in nine patients, considered as a recurrent stroke. To attribute a prognostic role to these lesions, clinical and neuroradiological follow-up needs to be continued. Springer-Verlag, 2011 Stroke nationallicence Young nationallicence Follow-up nationallicence Silent cerebral lesions nationallicence Patella Rosalba Azienda Ospedaliera Sant'Andrea, Stroke Unit, Neurologia II Facoltà di Medicina e Chirurgia Università di Roma "Sapienza”, Via di Grottarossa 1035, 00189, Rome, Italy aut Spalloni Alessandra Azienda Ospedaliera Sant'Andrea, Stroke Unit, Neurologia II Facoltà di Medicina e Chirurgia Università di Roma "Sapienza”, Via di Grottarossa 1035, 00189, Rome, Italy aut Ferrari Marco Azienda Ospedaliera Sant'Andrea, Stroke Unit, Neurologia II Facoltà di Medicina e Chirurgia Università di Roma "Sapienza”, Via di Grottarossa 1035, 00189, Rome, Italy aut La Starza Sara Azienda Ospedaliera Sant'Andrea, Stroke Unit, Neurologia II Facoltà di Medicina e Chirurgia Università di Roma "Sapienza”, Via di Grottarossa 1035, 00189, Rome, Italy aut Bozzao Alessandro Azienda Ospedaliera Sant'Andrea, Neuroradiologia II Facoltà di Medicina e Chirurgia Università di Roma "Sapienza”, Via di Grottarossa 1035, 00189, Rome, Italy aut Rasura Maurizia Azienda Ospedaliera Sant'Andrea, Stroke Unit, Neurologia II Facoltà di Medicina e Chirurgia Università di Roma "Sapienza”, Via di Grottarossa 1035, 00189, Rome, Italy aut Neurological Sciences Springer Milan 32/3(2011-06-01), 427-432 1590-1874 32:3<427 2011 32 10072 https://doi.org/10.1007/s10072-011-0507-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-011-0507-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Patella Rosalba Azienda Ospedaliera Sant'Andrea, Stroke Unit, Neurologia II Facoltà di Medicina e Chirurgia Università di Roma "Sapienza”, Via di Grottarossa 1035, 00189, Rome, Italy aut NATIONALLICENCE 700 1- Spalloni Alessandra Azienda Ospedaliera Sant'Andrea, Stroke Unit, Neurologia II Facoltà di Medicina e Chirurgia Università di Roma "Sapienza”, Via di Grottarossa 1035, 00189, Rome, Italy aut NATIONALLICENCE 700 1- Ferrari Marco Azienda Ospedaliera Sant'Andrea, Stroke Unit, Neurologia II Facoltà di Medicina e Chirurgia Università di Roma "Sapienza”, Via di Grottarossa 1035, 00189, Rome, Italy aut NATIONALLICENCE 700 1- La Starza Sara Azienda Ospedaliera Sant'Andrea, Stroke Unit, Neurologia II Facoltà di Medicina e Chirurgia Università di Roma "Sapienza”, Via di Grottarossa 1035, 00189, Rome, Italy aut NATIONALLICENCE 700 1- Bozzao Alessandro Azienda Ospedaliera Sant'Andrea, Neuroradiologia II Facoltà di Medicina e Chirurgia Università di Roma "Sapienza”, Via di Grottarossa 1035, 00189, Rome, Italy aut NATIONALLICENCE 700 1- Rasura Maurizia Azienda Ospedaliera Sant'Andrea, Stroke Unit, Neurologia II Facoltà di Medicina e Chirurgia Università di Roma "Sapienza”, Via di Grottarossa 1035, 00189, Rome, Italy aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/3(2011-06-01), 427-432 1590-1874 32:3<427 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer