caa a22 4500 445356790 CHVBK 20180317142902.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s10072-011-0803-1 doi (NATIONALLICENCE)springer-10.1007/s10072-011-0803-1 Infections in neuro-oncology [Elektronische Daten] [P. Gaviani, A. Silvani, E. Lamperti, A. Botturi, G. Simonetti, I. Milanesi, D. Ferrari, A. Salmaggi] Infections represent a serious and frequent complication in neuro-oncology patients. Decreased immune defences, along with poor nutritional status are the main predisposition factors. The combined therapeutic strategies of chemotherapy and radiotherapy may favour bone marrow depression and further increase the risk of developing opportunistic infections in brain tumour patients. The spectrum of infections in neuro-oncology patients is large and includes opportunistic infections by bacteria, viruses, fungi and parasites. Importantly, a high index of suspicion for opportunistic infections in general should be maintained, especially in glioma patients receiving dose-dense schedules of temozolomide. After neurosurgical procedures, infections most commonly present as meningitis, subdural empyema, or cerebral abscess. Infections represent a frequent and possibly serious complication in general immunocompromised oncology population. It should be underlined that infections are not limited to immunocompromised patients, being also present at the early disease stages, especially due to therapeutic strategies (chemo and radiotherapy, surgical procedures). Therefore this issue deserves more attention in neuroncology setting. Springer-Verlag, 2011 Glioma nationallicence Infections nationallicence Neuro-oncology nationallicence Gaviani P. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut Silvani A. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut Lamperti E. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut Botturi A. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut Simonetti G. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut Milanesi I. Department of Neurosurgery, U.O. Radiotherapy, Fondazione IRCCS Istituto Neurologico C. Besta, Milan, Italy aut Ferrari D. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut Salmaggi A. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut Neurological Sciences Springer Milan 32(2011-11-01), 233-236 1590-1874 32<233 2011 32 10072 https://doi.org/10.1007/s10072-011-0803-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-011-0803-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gaviani P. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut NATIONALLICENCE 700 1- Silvani A. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut NATIONALLICENCE 700 1- Lamperti E. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut NATIONALLICENCE 700 1- Botturi A. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut NATIONALLICENCE 700 1- Simonetti G. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut NATIONALLICENCE 700 1- Milanesi I. Department of Neurosurgery, U.O. Radiotherapy, Fondazione IRCCS Istituto Neurologico C. Besta, Milan, Italy aut NATIONALLICENCE 700 1- Ferrari D. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut NATIONALLICENCE 700 1- Salmaggi A. Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133, Milan, Italy aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32(2011-11-01), 233-236 1590-1874 32<233 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer