caa a22 4500 445357053 CHVBK 20180317142903.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s10072-011-0514-7 doi (NATIONALLICENCE)springer-10.1007/s10072-011-0514-7 Strio-pallido-dentate calcinosis: a diagnostic approach in adult patients [Elektronische Daten] [Sara Bonazza, Chiara La Morgia, Paolo Martinelli, Sabina Capellari] Familial idiopathic bilateral strio-pallido-dentate calcinosis is a rare autosomal dominant disorder characterized by massive symmetric calcification, detectable by CT, into the globus pallidus and striatum, with or without the involvement of the dentate nucleus, thalamus and white matter in the absence of alterations of calcium metabolism. Clinically, it has been associated with movement and/or neuropsychiatric disorders with age at onset typically in the fourth or fifth decade. Other sporadic or familial diseases can be responsible for brain calcifications with a similar anatomic strio-pallidal or strio-pallido-dentate pattern and, a restricted number of them, for neurological symptoms with onset in adulthood. Moreover, physiological age-related basal ganglia calcifications are often incidentally found, although with a far different CT aspect, in elderly patients with movement disorders. Indentifying familial and idiopathic cases may offer the opportunity to study the molecular mechanisms underlying this minerals deposition. Springer-Verlag, 2011 Basal ganglia nationallicence Strio-pallido-dentate nationallicence Familial-idiopathic-strio-pallido-dentate calcinosis nationallicence Calcifications nationallicence Fahr's disease nationallicence Bonazza Sara Dipartimento di Scienze Neurologiche, Università di Bologna, Via Foscolo 7, 40123, Bologna, Italy aut La Morgia Chiara Dipartimento di Scienze Neurologiche, Università di Bologna, Via Foscolo 7, 40123, Bologna, Italy aut Martinelli Paolo Dipartimento di Scienze Neurologiche, Università di Bologna, Via Foscolo 7, 40123, Bologna, Italy aut Capellari Sabina Dipartimento di Scienze Neurologiche, Università di Bologna, Via Foscolo 7, 40123, Bologna, Italy aut Neurological Sciences Springer Milan 32/4(2011-08-01), 537-545 1590-1874 32:4<537 2011 32 10072 https://doi.org/10.1007/s10072-011-0514-7 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-011-0514-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bonazza Sara Dipartimento di Scienze Neurologiche, Università di Bologna, Via Foscolo 7, 40123, Bologna, Italy aut NATIONALLICENCE 700 1- La Morgia Chiara Dipartimento di Scienze Neurologiche, Università di Bologna, Via Foscolo 7, 40123, Bologna, Italy aut NATIONALLICENCE 700 1- Martinelli Paolo Dipartimento di Scienze Neurologiche, Università di Bologna, Via Foscolo 7, 40123, Bologna, Italy aut NATIONALLICENCE 700 1- Capellari Sabina Dipartimento di Scienze Neurologiche, Università di Bologna, Via Foscolo 7, 40123, Bologna, Italy aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/4(2011-08-01), 537-545 1590-1874 32:4<537 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer