caa a22 4500 445357436 CHVBK 20180317142904.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10072-010-0471-6 doi (NATIONALLICENCE)springer-10.1007/s10072-010-0471-6 Acute transient inflammatory leukoencephalopathy in HIV [Elektronische Daten] [E. Tavazzi, L. Magrassi, A. Maccabruni, V. Bargiggia, A. Pichiecchio, S. Delbue, P. Ferrante, L. Minoli, E. Marchioni] HIV-related acute inflammatory leukoencephalopathy of undetermined origin (AIL) is characterized by abrupt onset of symptoms generally associated with focal brain lesions and inflammatory CSF findings. A previously asymptomatic 31-year-old HIV+ woman presented with acute cognitive difficulties, right hemiparesis and dysphasia. Brain MRI showed a large contrast-enhancing lesion in the left frontal lobe; brain biopsy revealed an inflammatory process. No etiological agent was found in blood, CSF or brain tissue. The patient was given systemic steroids and gammaglobulins and put on HAART. Clinical conditions progressively and completely recovered. Further brain MRI showed the shrinkage of the lesion with no contrast enhancement. Our case could be classified as AIL in HIV resembling ADEM pattern and highlights the importance of taking into consideration. ADEM in the diagnostic process of HIV-related leukoencephalopathy even if the typical features are lacking, as immunodeficiency could modify both presentation and disease course. Springer-Verlag, 2011 Acute leukoencephalopathy nationallicence ADEM nationallicence HIV nationallicence Tavazzi E. Department of General Neurology, IRCCS National Neurological Institute C. Mondino IRCCS, via Mondino 2, 27100, Pavia, Italy aut Magrassi L. Neurosurgery Department of Surgical Sciences, University of Pavia, "Policlinico San Matteo” IRCCS Foundation, Pavia, Italy aut Maccabruni A. Department of Infectious Diseases, "Policlinico San Matteo” IRCCS Foundation, Pavia, Italy aut Bargiggia V. Department of General Neurology, IRCCS National Neurological Institute C. Mondino IRCCS, via Mondino 2, 27100, Pavia, Italy aut Pichiecchio A. Neuroradiology Unit, IRCCS National Neurological Institute C. Mondino, Pavia, Italy aut Delbue S. Department of Public Health, Microbiology, Virology, University of Milan, Milan, Italy aut Ferrante P. Department of Public Health, Microbiology, Virology, University of Milan, Milan, Italy aut Minoli L. Department of Infectious Diseases, "Policlinico San Matteo” IRCCS Foundation, Pavia, Italy aut Marchioni E. Department of General Neurology, IRCCS National Neurological Institute C. Mondino IRCCS, via Mondino 2, 27100, Pavia, Italy aut Neurological Sciences Springer Milan 32/5(2011-10-01), 899-902 1590-1874 32:5<899 2011 32 10072 https://doi.org/10.1007/s10072-010-0471-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-010-0471-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tavazzi E. Department of General Neurology, IRCCS National Neurological Institute C. Mondino IRCCS, via Mondino 2, 27100, Pavia, Italy aut NATIONALLICENCE 700 1- Magrassi L. Neurosurgery Department of Surgical Sciences, University of Pavia, "Policlinico San Matteo” IRCCS Foundation, Pavia, Italy aut NATIONALLICENCE 700 1- Maccabruni A. Department of Infectious Diseases, "Policlinico San Matteo” IRCCS Foundation, Pavia, Italy aut NATIONALLICENCE 700 1- Bargiggia V. Department of General Neurology, IRCCS National Neurological Institute C. Mondino IRCCS, via Mondino 2, 27100, Pavia, Italy aut NATIONALLICENCE 700 1- Pichiecchio A. Neuroradiology Unit, IRCCS National Neurological Institute C. Mondino, Pavia, Italy aut NATIONALLICENCE 700 1- Delbue S. Department of Public Health, Microbiology, Virology, University of Milan, Milan, Italy aut NATIONALLICENCE 700 1- Ferrante P. Department of Public Health, Microbiology, Virology, University of Milan, Milan, Italy aut NATIONALLICENCE 700 1- Minoli L. Department of Infectious Diseases, "Policlinico San Matteo” IRCCS Foundation, Pavia, Italy aut NATIONALLICENCE 700 1- Marchioni E. Department of General Neurology, IRCCS National Neurological Institute C. Mondino IRCCS, via Mondino 2, 27100, Pavia, Italy aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/5(2011-10-01), 899-902 1590-1874 32:5<899 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer