caa a22 4500 445357479 CHVBK 20180317142905.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10072-011-0506-7 doi (NATIONALLICENCE)springer-10.1007/s10072-011-0506-7 Downbeat nystagmus, ataxia and spastic tetraparesis due to coeliac disease [Elektronische Daten] [Mario Habek, Iva Hojsak, Barbara Barun, Vesna Brinar] A 25-year-old female presented to a university neurology clinic with a 1-month history of progressive ataxia, downbeat nystagmus and spastic tetraparesis. Personal history revealed polyarthralgias and weight loss. Family history was negative. Following thorough history, laboratory, neurophysiological and MRI investigations, a diagnosis of cerebellar ataxia due to coeliac disease was done. The patient was treated with strict gluten-free diet and intravenous administration of immunoglobulins. Although there are many controversies about neurological manifestations of coeliac disease, this case pointed to strong association between these two disorders. The findings of elevated protein content in the cerebrospinal fluid with positive oligoclonal bands suggested an immune-mediated process, further supported by positive anti-endomysium antibodies and anti-transglutaminase antibodies in the cerebrospinal fluid. Springer-Verlag, 2011 Ataxia nationallicence Coeliac disease nationallicence Immunoglobulin A anti-endomysium antibodies nationallicence Immunoglobulin A anti-transglutaminase antibodies nationallicence Cerebrospinal fluid nationallicence Habek Mario Department of Neurology, School of Medicine, University of Zagreb, Zagreb, Croatia aut Hojsak Iva Department of Pediatrics, Referral Center for Pediatric Gastroenterology and Nutrition, Children's Hospital Zagreb, Zagreb, Croatia aut Barun Barbara Department of Neurology, School of Medicine, University of Zagreb, Zagreb, Croatia aut Brinar Vesna Department of Neurology, School of Medicine, University of Zagreb, Zagreb, Croatia aut Neurological Sciences Springer Milan 32/5(2011-10-01), 911-914 1590-1874 32:5<911 2011 32 10072 https://doi.org/10.1007/s10072-011-0506-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-011-0506-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Habek Mario Department of Neurology, School of Medicine, University of Zagreb, Zagreb, Croatia aut NATIONALLICENCE 700 1- Hojsak Iva Department of Pediatrics, Referral Center for Pediatric Gastroenterology and Nutrition, Children's Hospital Zagreb, Zagreb, Croatia aut NATIONALLICENCE 700 1- Barun Barbara Department of Neurology, School of Medicine, University of Zagreb, Zagreb, Croatia aut NATIONALLICENCE 700 1- Brinar Vesna Department of Neurology, School of Medicine, University of Zagreb, Zagreb, Croatia aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/5(2011-10-01), 911-914 1590-1874 32:5<911 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer