caa a22 4500 445357495 CHVBK 20180317142905.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10072-011-0636-y doi (NATIONALLICENCE)springer-10.1007/s10072-011-0636-y Resting-state brain networks: literature review and clinical applications [Elektronische Daten] [Cristina Rosazza, Ludovico Minati] This review focuses on resting-state functional connectivity, a functional MRI technique which allows the study of spontaneous brain activity generated under resting conditions. This approach is useful to explore the brain's functional organization and to examine if it is altered in neurological or psychiatric diseases. Resting-state functional connectivity has revealed a number of networks which are consistently found in healthy subjects and represent specific patterns of synchronous activity. In this review, we examine the behavioral, physiological and neurological evidences relevant to this coherent brain activity and, in particular, to each network. The investigation of functional connectivity appears promising from a clinical perspective, considering the amount of evidence regarding the importance of spontaneous activity and that resting-state paradigms are inherently simple to implement. We also discuss some examples of existing clinical applications, such as in Alzheimer's disease, and emerging possibilities such as in pre-operative mapping and disorders of consciousness. Springer-Verlag, 2011 Functional connectivity nationallicence Resting state nationallicence Spontaneous brain activity nationallicence Coherence nationallicence Cognitive correlates nationallicence Clinical applications nationallicence Rosazza Cristina Scientific Department, Fondazione IRCCS Istituto Neurologico "Carlo Besta”, via Celoria, 11, 20133, Milan, Italy aut Minati Ludovico Scientific Department, Fondazione IRCCS Istituto Neurologico "Carlo Besta”, via Celoria, 11, 20133, Milan, Italy aut Neurological Sciences Springer Milan 32/5(2011-10-01), 773-785 1590-1874 32:5<773 2011 32 10072 https://doi.org/10.1007/s10072-011-0636-y text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-011-0636-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rosazza Cristina Scientific Department, Fondazione IRCCS Istituto Neurologico "Carlo Besta”, via Celoria, 11, 20133, Milan, Italy aut NATIONALLICENCE 700 1- Minati Ludovico Scientific Department, Fondazione IRCCS Istituto Neurologico "Carlo Besta”, via Celoria, 11, 20133, Milan, Italy aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/5(2011-10-01), 773-785 1590-1874 32:5<773 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer