caa a22 4500 445358106 CHVBK 20180317142907.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10072-010-0396-0 doi (NATIONALLICENCE)springer-10.1007/s10072-010-0396-0 Oxygen cost of treadmill and over-ground walking in mildly disabled persons with multiple sclerosis [Elektronische Daten] [Robert Motl, Yoojin Suh, Deirdre Dlugonski, Madeline Weikert, Stamatis Agiovlasitis, Bo Fernhall, Myla Goldman] Walking impairment is a ubiquitous feature of multiple sclerosis (MS) and the O2 cost of walking might quantify this dysfunction in mild MS. This paper examined the difference in O2 cost of walking between persons with MS who have mild disability and healthy controls and the correlation between the O2 cost of walking and disability. Study 1 included 18 persons with mild MS and 18 controls and indicated that the O2 cost of walking was significantly higher in MS than controls and that disability was significantly associated with the O2 cost of slow, moderate, and fast treadmill walking. Study 2 included 24 persons with mild MS and indicated that disability was significantly correlated with O2 cost of comfortable, fast, and slow over-ground walking. We provide evidence that the O2 cost of walking is an indicator of walking dysfunction in mildly disabled persons with MS and should be considered in clinical research and practice. Springer-Verlag, 2010 Multiple sclerosis nationallicence Validity nationallicence Walking nationallicence Motl Robert Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., 61801, Urbana, IL, USA aut Suh Yoojin Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., 61801, Urbana, IL, USA aut Dlugonski Deirdre Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., 61801, Urbana, IL, USA aut Weikert Madeline Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., 61801, Urbana, IL, USA aut Agiovlasitis Stamatis Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., 61801, Urbana, IL, USA aut Fernhall Bo Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., 61801, Urbana, IL, USA aut Goldman Myla Department of Neurology, University of Virginia, PO Box 800394, 22958, Charlottesville, VA, USA aut Neurological Sciences Springer Milan 32/2(2011-04-01), 255-262 1590-1874 32:2<255 2011 32 10072 https://doi.org/10.1007/s10072-010-0396-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-010-0396-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Motl Robert Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., 61801, Urbana, IL, USA aut NATIONALLICENCE 700 1- Suh Yoojin Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., 61801, Urbana, IL, USA aut NATIONALLICENCE 700 1- Dlugonski Deirdre Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., 61801, Urbana, IL, USA aut NATIONALLICENCE 700 1- Weikert Madeline Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., 61801, Urbana, IL, USA aut NATIONALLICENCE 700 1- Agiovlasitis Stamatis Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., 61801, Urbana, IL, USA aut NATIONALLICENCE 700 1- Fernhall Bo Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 350 Freer Hall, 906 South Goodwin Ave., 61801, Urbana, IL, USA aut NATIONALLICENCE 700 1- Goldman Myla Department of Neurology, University of Virginia, PO Box 800394, 22958, Charlottesville, VA, USA aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/2(2011-04-01), 255-262 1590-1874 32:2<255 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer