caa a22 4500 445358114 CHVBK 20180317142907.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10072-010-0448-5 doi (NATIONALLICENCE)springer-10.1007/s10072-010-0448-5 Nocturnal frontal lobe epilepsy presenting with restless leg syndrome-like symptoms [Elektronische Daten] [Irene Aricò, Rosaria Condurso, Francesca Granata, Lino Nobili, Oliviero Bruni, Rosalia Silvestri] We describe the case of a 22-year-old male affected by NFLE reporting paroxysmal RLS-like symptoms. The patient was referred to our Sleep Center due to nocturnal paresthesias and cramps involving the left leg and leading to sleep fragmentation. At age 4, the patient presented with secondary generalized seizures preceded by left leg discomfort, controlled on CBZ. After successive therapy discontinuation, leg symptoms built up in frequency and duration until a secondary generalized seizure re-occurred. On CBZ prompt resumption no further GM seizures occurred albeit persistence of night-time frequent cramps and paraesthesia. Sleep EEG demonstrated asymmetric interictal sharp theta on the right posterior frontal areas, whereas brain MRI results were consistent with a Taylor type right frontal cortical dysplasia. CBZ augmentation and add on therapy with LEV led to further frequency reduction of sensory symptoms. Springer-Verlag, 2010 NFLE nationallicence RLS nationallicence Cortical dysplasia Taylor-type nationallicence Aricò Irene Department of Neurosciences, Sleep Medicine Center, Messina Medical School, Messina, Italy aut Condurso Rosaria Department of Neurosciences, Sleep Medicine Center, Messina Medical School, Messina, Italy aut Granata Francesca Department of Radiological Sciences, University of Messina, Messina, Italy aut Nobili Lino Centre of Epilepsy Surgery "C. Munari”, Center of Sleep Medicine, Niguarda Hospital, Milan, Italy aut Bruni Oliviero Department of Developmental Neurology and Psychiatry, Center for Pediatric Sleep Disorders, Rome, Italy aut Silvestri Rosalia Department of Neurosciences, Sleep Medicine Center, Messina Medical School, Messina, Italy aut Neurological Sciences Springer Milan 32/2(2011-04-01), 313-315 1590-1874 32:2<313 2011 32 10072 https://doi.org/10.1007/s10072-010-0448-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-010-0448-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Aricò Irene Department of Neurosciences, Sleep Medicine Center, Messina Medical School, Messina, Italy aut NATIONALLICENCE 700 1- Condurso Rosaria Department of Neurosciences, Sleep Medicine Center, Messina Medical School, Messina, Italy aut NATIONALLICENCE 700 1- Granata Francesca Department of Radiological Sciences, University of Messina, Messina, Italy aut NATIONALLICENCE 700 1- Nobili Lino Centre of Epilepsy Surgery "C. Munari”, Center of Sleep Medicine, Niguarda Hospital, Milan, Italy aut NATIONALLICENCE 700 1- Bruni Oliviero Department of Developmental Neurology and Psychiatry, Center for Pediatric Sleep Disorders, Rome, Italy aut NATIONALLICENCE 700 1- Silvestri Rosalia Department of Neurosciences, Sleep Medicine Center, Messina Medical School, Messina, Italy aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/2(2011-04-01), 313-315 1590-1874 32:2<313 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer