caa a22 4500 445358262 CHVBK 20180317142907.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10072-010-0460-9 doi (NATIONALLICENCE)springer-10.1007/s10072-010-0460-9 Aseptic meningitis after transsphenoidal management of Rathke's cleft cyst: case report and review of the literature [Elektronische Daten] [Maria Koutourousiou, Andreas Seretis] Aseptic meningitis after transsphenoidal surgery (TSS) for treatment of Rathke's cleft cyst (RCC) is a rare complication caused by the leakage of the cyst contents within the subarachnoid space. We present a case of aseptic meningitis occurring after TSS for a RCC. During surgery, the cyst wall was subtotally removed, and intraoperative cerebrospinal fluid (CSF) leakage was observed. The patient developed meningeal signs and symptoms on the first postoperative day. CSF examinations were highly suggestive of aseptic meningitis. Histological examination confirmed a granulomatous inflammatory reaction of the RCC wall. Preexisting inflammation, subtotal cyst wall resection, intraoperative erosion of the diaphragma sellae and placement of a lumbar drain may be risk factors for the development of aseptic meningitis. Springer-Verlag, 2010 Aseptic meningitis nationallicence Cerebrospinal fluid nationallicence Rathke's cleft cyst nationallicence Transsphenoidal surgery nationallicence Koutourousiou Maria Department of Neurosurgery, Athens General Hospital "G. Gennimatas”, 154 Messogion Ave, 115 27, Athens, Greece aut Seretis Andreas Department of Neurosurgery, Athens General Hospital "G. Gennimatas”, 154 Messogion Ave, 115 27, Athens, Greece aut Neurological Sciences Springer Milan 32/2(2011-04-01), 323-326 1590-1874 32:2<323 2011 32 10072 https://doi.org/10.1007/s10072-010-0460-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-010-0460-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Koutourousiou Maria Department of Neurosurgery, Athens General Hospital "G. Gennimatas”, 154 Messogion Ave, 115 27, Athens, Greece aut NATIONALLICENCE 700 1- Seretis Andreas Department of Neurosurgery, Athens General Hospital "G. Gennimatas”, 154 Messogion Ave, 115 27, Athens, Greece aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/2(2011-04-01), 323-326 1590-1874 32:2<323 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer