caa a22 4500 445358289 CHVBK 20180317142907.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10072-010-0444-9 doi (NATIONALLICENCE)springer-10.1007/s10072-010-0444-9 Scintigraphic, neuroradiological and clinical comparison in two patients with primary sporadic and two with secondary Fahr's disease [Elektronische Daten] [Giovanni Caranci, Giovanni Grillea, Francesco Barbato, Alexandra Brunetti, Tiziana Tassinari, Mariarita Di Ruzza, Francesco Lena, Barbara Gandolfi, Anna Castellano, Marcello Bartolo, Claudio Colonnese, Nicola Modugno, Stefano Ruggieri, Mario Manfredi] Bilateral striopallidodentate calcification, usually termed Fahr's disease, can give rise to various clinical manifestations including hyperkinetic movement disorders or a hypokinetic Parkinsonian syndrome, behavioural and mood changes, cognitive deficits and even frank dementia. We describe four patients all of whom underwent a detailed scintigraphic, neuroradiological and clinical work-up: two had primary, sporadic Fahr's disease and two had Fahr's disease secondary to hypoparathyroidism. The neuroradiological and clinical studies disclosed similar anatomical and pathological changes in the four patients but variable and sometimes unexpected clinical manifestations. Both patients with primary forms had hypokinetic Parkinsonian syndrome, both patients with secondary forms had hyperkinetic movements. Dopamine autotransporter scan brain scintigraphy disclosed an unexpected unilateral putamen involvement despite substantially symmetric calcifications. Springer-Verlag, 2010 Fahr's disease nationallicence Functional imaging nationallicence Hyperkinetic movements nationallicence Hypoparathyroidism nationallicence Caranci Giovanni Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut Grillea Giovanni Section of Neuroradiology, IRCCS Neuromed Institute, 86077, Pozzilli (IS), Italy aut Barbato Francesco Section of Nuclear Medicine, IRCCS Neuromed Institute, 86077, Pozzilli (IS), Italy aut Brunetti Alexandra Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut Tassinari Tiziana Division of Neurology, Santa Corona Hospital, Pietra Ligure (SV), Italy aut Di Ruzza Mariarita Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut Lena Francesco Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut Gandolfi Barbara Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut Castellano Anna Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut Bartolo Marcello Section of Neuroradiology, IRCCS Neuromed Institute, 86077, Pozzilli (IS), Italy aut Colonnese Claudio Section of Neuroradiology, IRCCS Neuromed Institute, 86077, Pozzilli (IS), Italy aut Modugno Nicola Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut Ruggieri Stefano Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut Manfredi Mario Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut Neurological Sciences Springer Milan 32/2(2011-04-01), 337-341 1590-1874 32:2<337 2011 32 10072 https://doi.org/10.1007/s10072-010-0444-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10072-010-0444-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Caranci Giovanni Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 700 1- Grillea Giovanni Section of Neuroradiology, IRCCS Neuromed Institute, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 700 1- Barbato Francesco Section of Nuclear Medicine, IRCCS Neuromed Institute, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 700 1- Brunetti Alexandra Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 700 1- Tassinari Tiziana Division of Neurology, Santa Corona Hospital, Pietra Ligure (SV), Italy aut NATIONALLICENCE 700 1- Di Ruzza Mariarita Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 700 1- Lena Francesco Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 700 1- Gandolfi Barbara Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 700 1- Castellano Anna Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 700 1- Bartolo Marcello Section of Neuroradiology, IRCCS Neuromed Institute, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 700 1- Colonnese Claudio Section of Neuroradiology, IRCCS Neuromed Institute, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 700 1- Modugno Nicola Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 700 1- Ruggieri Stefano Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 700 1- Manfredi Mario Division of Neurology, IRCCS Neuromed Institute, Via Atinense 18, 86077, Pozzilli (IS), Italy aut NATIONALLICENCE 773 0- Neurological Sciences Springer Milan 32/2(2011-04-01), 337-341 1590-1874 32:2<337 2011 32 10072 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer