caa a22 4500 445363908 CHVBK 20180317142923.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s10397-011-0674-8 doi (NATIONALLICENCE)springer-10.1007/s10397-011-0674-8 Treatment options for dysfunctional uterine bleeding: evaluation of clinical results [Elektronische Daten] [George Pados, Dimitrios Athanatos, Dimitrios Tsolakidis, Panagiotis Stamatopoulos, Basil Tarlatzis] Abnormal uterine bleeding is one of the most common problems in women of reproductive age, and dysfunctional uterine bleeding (DUB) accounts for about half the cases. The aim of this review is to present all treatment options for women suffering from DUB and to evaluate their effectiveness. A detailed search strategy on electronic databases was carried out to identify trials and reviews on management of abnormal uterine bleeding. Tranexamic acid is the most effective medical treatment. A levonorgestrel-releasing intrauterine device is a low-cost, simple, and effective medical method, comparable to hysterectomy in terms of quality of life. In cases of DUB resistant to medical treatment, surgical treatment should be offered. First-generation ablation techniques are effective, but have a long learning curve. Second-generation ablation devices are highly effective and safe alternatives, thoroughly compared to first-generation techniques. Hysterectomy is the only method that guarantees treatment of dysfunctional uterine bleeding, but is a major operation associated with higher morbidity and mortality rates. Proper counseling of each woman with DUB regarding all treatment modalities can provide the best choice for each patient. More prospective randomized trials are needed to establish the effectiveness of these methods Springer-Verlag, 2011 Dysfunctional uterine bleeding nationallicence Ablation nationallicence Menorrhagia nationallicence Hysteroscopy nationallicence Pados George First Department OB-GYN, Aristotle University, Thessaloniki, Greece aut Athanatos Dimitrios First Department OB-GYN, Aristotle University, Thessaloniki, Greece aut Tsolakidis Dimitrios First Department OB-GYN, Aristotle University, Thessaloniki, Greece aut Stamatopoulos Panagiotis First Department OB-GYN, Aristotle University, Thessaloniki, Greece aut Tarlatzis Basil First Department OB-GYN, Aristotle University, Thessaloniki, Greece aut Gynecological Surgery Springer-Verlag 8/4(2011-11-01), 385-393 1613-2076 8:4<385 2011 8 10397 https://doi.org/10.1007/s10397-011-0674-8 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10397-011-0674-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pados George First Department OB-GYN, Aristotle University, Thessaloniki, Greece aut NATIONALLICENCE 700 1- Athanatos Dimitrios First Department OB-GYN, Aristotle University, Thessaloniki, Greece aut NATIONALLICENCE 700 1- Tsolakidis Dimitrios First Department OB-GYN, Aristotle University, Thessaloniki, Greece aut NATIONALLICENCE 700 1- Stamatopoulos Panagiotis First Department OB-GYN, Aristotle University, Thessaloniki, Greece aut NATIONALLICENCE 700 1- Tarlatzis Basil First Department OB-GYN, Aristotle University, Thessaloniki, Greece aut NATIONALLICENCE 773 0- Gynecological Surgery Springer-Verlag 8/4(2011-11-01), 385-393 1613-2076 8:4<385 2011 8 10397 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer