caa a22 4500 445363932 CHVBK 20180317142923.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s10397-011-0660-1 doi (NATIONALLICENCE)springer-10.1007/s10397-011-0660-1 Long-term follow-up after laparoscopic management of endometrial cancer: a 15-year cohort study [Elektronische Daten] [Benoit Rabischong, Demetrio Larraín, Guillaume Le Bouëdec, Michel Canis, Christophe Pomel, Kris Jardon, Fabrice Kwiatkowski, Jean-Louis Achard, Jacques Dauplat, Gerard Mage] The objective of this study was to evaluate long-term oncological outcomes of laparoscopic management of endometrial carcinoma (EC) in a large series of consecutive patients from two referral cancer centres. The study is a large retrospective study with 15-year follow-up. The clinical records of 207 consecutive women with clinical stage I EC managed by laparoscopy between 1990 and 2005 were reviewed. Laparoscopy included peritoneal washing, inspection of abdominal cavity, total laparoscopic hysterectomy + bilateral salpingo-oophorectomy and pelvic/para-aortic lymphadenectomy depending on the preoperative histology or frozen section results. Data collected included conversion rate, operative time, hospital stay, surgical complications, FIGO 1988 stage and 5-year survival. Laparoscopic procedures were converted to laparotomy in nine (4.3%) cases. Mean operative time was 173.2min (70-300min). Mean hospital stay was 5days. The mean number of lymph nodes removed was 10 (2-25). Lymphadenectomy was considered not feasible in 20 cases (12.9%) due to technical difficulties. Intraoperative and postoperative complications were seen in 11 (5.6%) and 13 (6.6%) women, respectively. Histopathological results led to upstaging in 11.6% of cases. After a mean follow-up of 74.8months (14-204months), 5-year cause-specific and disease-free survival rates were 93.2% and 89.3%, respectively. Twenty-one (10.6%) patients developed recurrences. No port site metastases were identified. Laparoscopic management of EC is feasible, reproducible and does not worsen patient prognosis. It allows comprehensive surgical staging and the option of lymphadenectomy in a single surgical procedure without compromising the oncological radicality required. Our results show minimal morbidity and similar long-term outcomes than those obtained by laparotomy in the literature. Springer-Verlag, 2011 Endometrial cancer nationallicence Laparoscopy nationallicence Long-term follow-up nationallicence Survival nationallicence Rabischong Benoit Department of Obstetrics-Gynecology and Human Reproduction, CHU Estaing, 1 Place Lucie Aubrac, 63003, Clermont-Ferrand, France aut Larraín Demetrio Department of Obstetrics-Gynecology and Human Reproduction, CHU Estaing, 1 Place Lucie Aubrac, 63003, Clermont-Ferrand, France aut Le Bouëdec Guillaume Department of Gynecologic Oncology and Surgery, Jean Perrin Cancer Center, 58 rue Montalembert, 63011, Clermont-Ferrand, France aut Canis Michel Department of Obstetrics-Gynecology and Human Reproduction, CHU Estaing, 1 Place Lucie Aubrac, 63003, Clermont-Ferrand, France aut Pomel Christophe Department of Gynecologic Oncology and Surgery, Jean Perrin Cancer Center, 58 rue Montalembert, 63011, Clermont-Ferrand, France aut Jardon Kris Department of Obstetrics-Gynecology and Human Reproduction, CHU Estaing, 1 Place Lucie Aubrac, 63003, Clermont-Ferrand, France aut Kwiatkowski Fabrice Department of Medical Research and Biostatistics, Jean Perrin Cancer Center, 58 rue Montalembert, 63011, Clermont-Ferrand, France aut Achard Jean-Louis Department of Gynecologic Oncology and Surgery, Jean Perrin Cancer Center, 58 rue Montalembert, 63011, Clermont-Ferrand, France aut Dauplat Jacques Department of Gynecologic Oncology and Surgery, Jean Perrin Cancer Center, 58 rue Montalembert, 63011, Clermont-Ferrand, France aut Mage Gerard Department of Obstetrics-Gynecology and Human Reproduction, CHU Estaing, 1 Place Lucie Aubrac, 63003, Clermont-Ferrand, France aut Gynecological Surgery Springer-Verlag 8/4(2011-11-01), 417-426 1613-2076 8:4<417 2011 8 10397 https://doi.org/10.1007/s10397-011-0660-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10397-011-0660-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rabischong Benoit Department of Obstetrics-Gynecology and Human Reproduction, CHU Estaing, 1 Place Lucie Aubrac, 63003, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Larraín Demetrio Department of Obstetrics-Gynecology and Human Reproduction, CHU Estaing, 1 Place Lucie Aubrac, 63003, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Le Bouëdec Guillaume Department of Gynecologic Oncology and Surgery, Jean Perrin Cancer Center, 58 rue Montalembert, 63011, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Canis Michel Department of Obstetrics-Gynecology and Human Reproduction, CHU Estaing, 1 Place Lucie Aubrac, 63003, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Pomel Christophe Department of Gynecologic Oncology and Surgery, Jean Perrin Cancer Center, 58 rue Montalembert, 63011, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Jardon Kris Department of Obstetrics-Gynecology and Human Reproduction, CHU Estaing, 1 Place Lucie Aubrac, 63003, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Kwiatkowski Fabrice Department of Medical Research and Biostatistics, Jean Perrin Cancer Center, 58 rue Montalembert, 63011, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Achard Jean-Louis Department of Gynecologic Oncology and Surgery, Jean Perrin Cancer Center, 58 rue Montalembert, 63011, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Dauplat Jacques Department of Gynecologic Oncology and Surgery, Jean Perrin Cancer Center, 58 rue Montalembert, 63011, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Mage Gerard Department of Obstetrics-Gynecology and Human Reproduction, CHU Estaing, 1 Place Lucie Aubrac, 63003, Clermont-Ferrand, France aut NATIONALLICENCE 773 0- Gynecological Surgery Springer-Verlag 8/4(2011-11-01), 417-426 1613-2076 8:4<417 2011 8 10397 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer