caa a22 4500 445364017 CHVBK 20180317142924.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s10397-011-0668-6 doi (NATIONALLICENCE)springer-10.1007/s10397-011-0668-6 Total laparoscopic hysterectomy versus total abdominal hysterectomy with bilateral salpingo-oophorectomy for endometrial carcinoma: a randomised controlled trial with 5-year follow-up [Elektronische Daten] [Kirsten Kluivers, Florien Ten Cate, Marlies Bongers, Hans Brölmann, Jan Hendriks] This report is on recovery and long-term outcomes in a small-scale randomised controlled trial (RCT) after total laparoscopic hysterectomy versus total abdominal hysterectomy in (potential) endometrial carcinoma patients. An RCT was performed among women with atypical endometrial hyperplasia and endometrial carcinoma scheduled for hysterectomy in a teaching hospital in The Netherlands. Women were randomised to total laparoscopic hysterectomy versus total abdominal hysterectomy both with bilateral salpingo-oophorectomy and were followed until 5years after the intervention. Patients completed the RAND 36-Item Short Form Health Survey (RAND-36), Quality of Recovery-40 (QoR-40) and Recovery Index-10 (RI-10) until 12weeks after surgery. Main outcome measure was quality of life and recovery in the first 12weeks after surgery. A linear mixed model was used for statistical analysis while accounting for baseline values where applicable. Seventeen women were included, of whom 11 allocated to the laparoscopic arm and 6 to the abdominal arm. Laparoscopic hysterectomy performed better on all scales and subscales used in the study. A statistically significant treatment effect, favouring laparoscopic hysterectomy, was found in the total RAND-36 (difference between groups 142 units, 95% confidence interval 46; 236). Clinical follow-up was completed after median 60months, but this study was too small for conclusions regarding the safety and survival. Laparoscopic hysterectomy results in better postoperative quality of life in the first 12weeks after surgery when compared with abdominal hysterectomy. The Author(s), 2011 Abdominal hysterectomy nationallicence Endometrial carcinoma nationallicence Laparoscopic hysterectomy nationallicence Randomised nationallicence Recovery nationallicence Quality of life nationallicence Kluivers Kirsten Department of Obstetrics & Gynaecology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands aut Ten Cate Florien Department of Obstetrics & Gynaecology, Máxima Medical Centre, De Run 4600, 5504 DB, Veldhoven, The Netherlands aut Bongers Marlies Department of Obstetrics & Gynaecology, Máxima Medical Centre, De Run 4600, 5504 DB, Veldhoven, The Netherlands aut Brölmann Hans Department of Obstetrics & Gynaecology, VU University Medical Centre, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands aut Hendriks Jan Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands aut Gynecological Surgery Springer-Verlag 8/4(2011-11-01), 427-434 1613-2076 8:4<427 2011 8 10397 https://doi.org/10.1007/s10397-011-0668-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10397-011-0668-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kluivers Kirsten Department of Obstetrics & Gynaecology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands aut NATIONALLICENCE 700 1- Ten Cate Florien Department of Obstetrics & Gynaecology, Máxima Medical Centre, De Run 4600, 5504 DB, Veldhoven, The Netherlands aut NATIONALLICENCE 700 1- Bongers Marlies Department of Obstetrics & Gynaecology, Máxima Medical Centre, De Run 4600, 5504 DB, Veldhoven, The Netherlands aut NATIONALLICENCE 700 1- Brölmann Hans Department of Obstetrics & Gynaecology, VU University Medical Centre, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Hendriks Jan Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands aut NATIONALLICENCE 773 0- Gynecological Surgery Springer-Verlag 8/4(2011-11-01), 427-434 1613-2076 8:4<427 2011 8 10397 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer