caa a22 4500 445368527 CHVBK 20180317142938.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00340-010-4300-7 doi (NATIONALLICENCE)springer-10.1007/s00340-010-4300-7 Optically stimulated heating using Nd3+ doped NaYF4 colloidal near infrared nanophosphors [Elektronische Daten] [A. Bednarkiewicz, D. Wawrzynczyk, M. Nyk, W. Strek] Although efficient in heat generation, gold nanoparticles dedicated for photostimulated localized hyperthermia treatment (LHT) lack luminescent properties suitable for detection in heterogeneous and autofluorescent tissue. Here, we study and report the use of bifunctional luminescent neodymium (Nd3+) ions doped α-NaYF4 colloidal nanoparticles as potential nanoheaters suitable for LHT. Up to 35°C (0.8°C/mW@514.5nm) temperature rise in ∼0.5ml colloidal 25%Nd3+:NaYF4 solution was achieved in comparison to around a 4°C rise for the undoped colloidal NaYF4. The maximum temperature (T max ) was linearly proportional to the concentration of Nd3+ dopant. The time required to elevate temperature to 1/e×T max  varied from 100 to 135 seconds. The proposed approach gives premises to the construction of multi-functional therapeutic agents detectable by means of fluorescence molecular imaging. The Author(s), 2010 Bednarkiewicz A. Institute of Low Temperature and Structure Research, PAN, ul. Okolna 2, 50-422, Wroclaw, Poland aut Wawrzynczyk D. Institute of Physical and Theoretical Chemistry, Department of Chemistry, Wrocław University of Technology, ul. Wybrzeże Wyspiańskiego 27, 50-370, Wroclaw, Poland aut Nyk M. Institute of Physical and Theoretical Chemistry, Department of Chemistry, Wrocław University of Technology, ul. Wybrzeże Wyspiańskiego 27, 50-370, Wroclaw, Poland aut Strek W. Institute of Low Temperature and Structure Research, PAN, ul. Okolna 2, 50-422, Wroclaw, Poland aut Applied Physics B Springer-Verlag 103/4(2011-06-01), 847-852 0946-2171 103:4<847 2011 103 340 https://doi.org/10.1007/s00340-010-4300-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00340-010-4300-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bednarkiewicz A. Institute of Low Temperature and Structure Research, PAN, ul. Okolna 2, 50-422, Wroclaw, Poland aut NATIONALLICENCE 700 1- Wawrzynczyk D. Institute of Physical and Theoretical Chemistry, Department of Chemistry, Wrocław University of Technology, ul. Wybrzeże Wyspiańskiego 27, 50-370, Wroclaw, Poland aut NATIONALLICENCE 700 1- Nyk M. Institute of Physical and Theoretical Chemistry, Department of Chemistry, Wrocław University of Technology, ul. Wybrzeże Wyspiańskiego 27, 50-370, Wroclaw, Poland aut NATIONALLICENCE 700 1- Strek W. Institute of Low Temperature and Structure Research, PAN, ul. Okolna 2, 50-422, Wroclaw, Poland aut NATIONALLICENCE 773 0- Applied Physics B Springer-Verlag 103/4(2011-06-01), 847-852 0946-2171 103:4<847 2011 103 340 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer