caa a22 4500 445370769 CHVBK 20180317142945.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s00340-011-4678-x doi (NATIONALLICENCE)springer-10.1007/s00340-011-4678-x Experimental and Monte Carlo investigation of visible diffuse-reflectance imaging sensitivity to diffusing particle size changes in an optical model of a bladder wall [Elektronische Daten] [N. Kalyagina, V. Loschenov, D. Wolf, C. Daul, W. Blondel, T. Savelieva] We have investigated the influence of scatterer size changes on the laser light diffusion, induced by collimated monochromatic laser irradiation, in tissue-like optical phantoms using diffuse-reflectance imaging. For that purpose, three-layer optical phantoms were prepared, in which nano- and microsphere size varied in order to simulate the scattering properties of healthy and cancerous urinary bladder walls. The informative areas of the surface diffuse-reflected light distributions were about 15×18 pixels for the smallest scattering particles of 0.05μm, about 21×25 pixels for the medium-size particles of 0.53μm, and about 25×30 pixels for the largest particles of 5.09μm. The computation of the laser spot areas provided useful information for the analysis of the light distribution with high measurement accuracy of up to92%. The minimal stability of78% accuracy was observed for superficial scattering signals on the phantoms with the largest particles. The experimental results showed a good agreement with the results obtained by the Monte Carlo simulations. The presented method shows a good potential to be useful for a tissue-state diagnosis of the urinary bladder. Springer-Verlag, 2011 Kalyagina N. Prokhorov General Physics Institute, Russian Academy of Sciences, Vavilov Str. 38, 119991, Moscow, Russia aut Loschenov V. Prokhorov General Physics Institute, Russian Academy of Sciences, Vavilov Str. 38, 119991, Moscow, Russia aut Wolf D. Centre de Recherche en Automatique de Nancy (CRAN UMR 7039), Nancy University, CNRS, 2 avenue de la forêt de Haye, 54516, Vandœuve-Les-Nancy, France aut Daul C. Centre de Recherche en Automatique de Nancy (CRAN UMR 7039), Nancy University, CNRS, 2 avenue de la forêt de Haye, 54516, Vandœuve-Les-Nancy, France aut Blondel W. Centre de Recherche en Automatique de Nancy (CRAN UMR 7039), Nancy University, CNRS, 2 avenue de la forêt de Haye, 54516, Vandœuve-Les-Nancy, France aut Savelieva T. Prokhorov General Physics Institute, Russian Academy of Sciences, Vavilov Str. 38, 119991, Moscow, Russia aut Applied Physics B Springer-Verlag 105/3(2011-11-01), 631-639 0946-2171 105:3<631 2011 105 340 https://doi.org/10.1007/s00340-011-4678-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00340-011-4678-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kalyagina N. Prokhorov General Physics Institute, Russian Academy of Sciences, Vavilov Str. 38, 119991, Moscow, Russia aut NATIONALLICENCE 700 1- Loschenov V. Prokhorov General Physics Institute, Russian Academy of Sciences, Vavilov Str. 38, 119991, Moscow, Russia aut NATIONALLICENCE 700 1- Wolf D. Centre de Recherche en Automatique de Nancy (CRAN UMR 7039), Nancy University, CNRS, 2 avenue de la forêt de Haye, 54516, Vandœuve-Les-Nancy, France aut NATIONALLICENCE 700 1- Daul C. Centre de Recherche en Automatique de Nancy (CRAN UMR 7039), Nancy University, CNRS, 2 avenue de la forêt de Haye, 54516, Vandœuve-Les-Nancy, France aut NATIONALLICENCE 700 1- Blondel W. Centre de Recherche en Automatique de Nancy (CRAN UMR 7039), Nancy University, CNRS, 2 avenue de la forêt de Haye, 54516, Vandœuve-Les-Nancy, France aut NATIONALLICENCE 700 1- Savelieva T. Prokhorov General Physics Institute, Russian Academy of Sciences, Vavilov Str. 38, 119991, Moscow, Russia aut NATIONALLICENCE 773 0- Applied Physics B Springer-Verlag 105/3(2011-11-01), 631-639 0946-2171 105:3<631 2011 105 340 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer