caa a22 4500 445372958 CHVBK 20180317142953.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00540-010-1072-5 doi (NATIONALLICENCE)springer-10.1007/s00540-010-1072-5 Preoperative depression is a risk factor for postoperative short-term and long-term cognitive dysfunction in patients with diabetes mellitus [Elektronische Daten] [Yuji Kadoi, Chikara Kawauchi, Masanobu Ide, Masataka Kuroda, Kenichiro Takahashi, Shigeru Saito, Nao Fujita, Akio Mizutani] Purpose: To identify whether the presence of preoperative depression in patients with diabetes mellitus is a risk factor for postoperative cognitive dysfunction after coronary artery bypass graft (CABG) surgery. Methods: Data from 90 patients with diabetes mellitus undergoing elective CABG were analyzed. Hemodynamic data (arterial and jugular venous blood gas values) were measured during cardiopulmonary bypass. Preoperatively, all patients were given the 21-item Beck depression inventory to identify the presence of depression. In addition, all patients underwent a battery of neurological and neuropsychological tests the day before surgery, 7days after surgery, and 6months after surgery. Results: The rate of cognitive dysfunction was 50% at 7days and 23% at 6months after surgery. Age, hypertension, presence of depression, duration of SjvO2≤50%, ascending aorta atherosclerosis, diabetic retinopathy, and insulin therapy were independent predictors of short-term cognitive dysfunction, whereas HbA1c, diabetic retinopathy, insulin therapy, and presence of depression were independent predictors of long-term cognitive dysfunction. Conclusions: We found that the presence of depression preoperatively is associated with short-term and long-term postoperative cognitive dysfunction in patients with diabetes mellitus. Japanese Society of Anesthesiologists, 2010 Diabetes mellitus nationallicence Cognitive dysfunction nationallicence Depression nationallicence Predictor nationallicence Kadoi Yuji Department of Anesthesiology, Gunma University School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Kawauchi Chikara Department of Anesthesiology, Gunma University School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Ide Masanobu Department of Anesthesiology, Gunma University School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Kuroda Masataka Department of Anesthesiology, Gunma University School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Takahashi Kenichiro Department of Anesthesiology, Gunma University School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Saito Shigeru Department of Anesthesiology, Gunma University School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Fujita Nao Department of Anesthesia, Keiyu Orthopedic Hospital, Tatehayashi, Gunma, Japan aut Mizutani Akio Department of Anesthesiology, Oita University Graduate School of Medicine, Oita, Japan aut Journal of Anesthesia Springer Japan 25/1(2011-02-01), 10-17 0913-8668 25:1<10 2011 25 540 https://doi.org/10.1007/s00540-010-1072-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00540-010-1072-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kadoi Yuji Department of Anesthesiology, Gunma University School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Kawauchi Chikara Department of Anesthesiology, Gunma University School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Ide Masanobu Department of Anesthesiology, Gunma University School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Kuroda Masataka Department of Anesthesiology, Gunma University School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Takahashi Kenichiro Department of Anesthesiology, Gunma University School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Saito Shigeru Department of Anesthesiology, Gunma University School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Fujita Nao Department of Anesthesia, Keiyu Orthopedic Hospital, Tatehayashi, Gunma, Japan aut NATIONALLICENCE 700 1- Mizutani Akio Department of Anesthesiology, Oita University Graduate School of Medicine, Oita, Japan aut NATIONALLICENCE 773 0- Journal of Anesthesia Springer Japan 25/1(2011-02-01), 10-17 0913-8668 25:1<10 2011 25 540 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer