caa a22 4500 445373180 CHVBK 20180317142954.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00540-011-1210-8 doi (NATIONALLICENCE)springer-10.1007/s00540-011-1210-8 Acute kidney injury during aortic arch surgery under deep hypothermic circulatory arrest [Elektronische Daten] [Yosuke Mori, Nobukazu Sato, Yoshiro Kobayashi, Ryoichi Ochiai] Purpose: The aim of this investigation was to describe the renal outcome and to identify risk factors for acute kidney injury (AKI), as defined by the Acute Kidney Injury Network (AKIN), during aortic arch surgery (AAS) under deep hypothermic circulatory arrest (DHCA). Methods: A retrospective and observational study has been performed. One hundred thirty-five patients requiring AAS under DHCA were studied. Results: Seventy-one patients (52.6%) developed AKI during the postoperative period. A logistic regression analysis identified three independent risk factors for AKI: preoperative hypertension (HT), emergency surgery, and duration of DHCA. Renal replacement therapy (RRT) was required in four patients (3.0%). The postoperative mortality rate among the patients with AKI was 2.8%, which was not statistically different from the rate of 1.6% observed in the non-AKI group (P=0.62). Conclusions: A high incidence of AKI during AAS under DHCA was confirmed. Because AKI is highly associated with aortic surgery, novel approaches for protecting the kidneys other than deep hypothermia are needed. The logistic regression model identified HT, emergency surgery, and duration of DHCA as independent risk factors for AKI. Japanese Society of Anesthesiologists, 2011 Acute kidney injury nationallicence Aortic arch surgery nationallicence Deep hypothermic circulatory arrest nationallicence Emergency surgery nationallicence Hypertension nationallicence Mori Yosuke The First Department of Anesthesiology, Toho University, School of Medicine, 6-11-1, Ohmori-Nishi, Ohta-ku, 143-8541, Tokyo, Japan aut Sato Nobukazu The First Department of Anesthesiology, Toho University, School of Medicine, 6-11-1, Ohmori-Nishi, Ohta-ku, 143-8541, Tokyo, Japan aut Kobayashi Yoshiro Department of Anesthesia, National Hospital Organization Tokyo Medical Center, Tokyo, Japan aut Ochiai Ryoichi The First Department of Anesthesiology, Toho University, School of Medicine, 6-11-1, Ohmori-Nishi, Ohta-ku, 143-8541, Tokyo, Japan aut Journal of Anesthesia Springer Japan 25/6(2011-12-01), 799-804 0913-8668 25:6<799 2011 25 540 https://doi.org/10.1007/s00540-011-1210-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00540-011-1210-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mori Yosuke The First Department of Anesthesiology, Toho University, School of Medicine, 6-11-1, Ohmori-Nishi, Ohta-ku, 143-8541, Tokyo, Japan aut NATIONALLICENCE 700 1- Sato Nobukazu The First Department of Anesthesiology, Toho University, School of Medicine, 6-11-1, Ohmori-Nishi, Ohta-ku, 143-8541, Tokyo, Japan aut NATIONALLICENCE 700 1- Kobayashi Yoshiro Department of Anesthesia, National Hospital Organization Tokyo Medical Center, Tokyo, Japan aut NATIONALLICENCE 700 1- Ochiai Ryoichi The First Department of Anesthesiology, Toho University, School of Medicine, 6-11-1, Ohmori-Nishi, Ohta-ku, 143-8541, Tokyo, Japan aut NATIONALLICENCE 773 0- Journal of Anesthesia Springer Japan 25/6(2011-12-01), 799-804 0913-8668 25:6<799 2011 25 540 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer