caa a22 4500 445373342 CHVBK 20180317142954.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00540-011-1225-1 doi (NATIONALLICENCE)springer-10.1007/s00540-011-1225-1 Assessment of cardiac preload status by pulse pressure variation in patients after anesthesia induction: comparison with central venous pressure and initial distribution volume of glucose [Elektronische Daten] [Zhiyong He, Hui Qiao, Wei Zhou, Yun Wang, Zhendong Xu, Xuehua Che, Jun Zhang, Weimin Liang] Purpose: Recognition of intraoperative hypovolemia is important for fluid management. Previous studies demonstrated functional preload parameter pulse pressure variation (PPV) could predict volume changes in response to fluid loading and loss. In this study, we examined the correlation between PPV and other two cardiac preload indicators, central venous pressure (CVP) or initial distribution volume of glucose (IDVG), in patients after anesthesia induction. Methods: In 30 patients undergoing scheduled craniotomy surgery, we compared measurement of PPV (%) using the Ohmeda monitor method to simultaneously measure CVP and IDVG after anesthesia induction through correlation analysis and receiver operating characteristic (ROC) curves. Results: Pulse pressure variation has negative linear correlation with IDVG (r=−0.65, P<0.01). IDVG values (n=13) when PPV≥11% showed a significant difference compared with those (n=17) when PPV<11% (P<0.001). The ROC curve showed the best cutoff value of IDVG is 122ml/kg, equivalent to the threshold of PPV (11%) for predicting fluid responsiveness. However, there is no significant correlation between CVP in normal ranges (4-9mmHg) and PPV (r=−0.12, P>0.05). Conclusion: As an indicator of cardiac preload, PPV has a negative linear correlation with IDVG in patients after anesthesia induction. It does not correlate well with CVP in the normal range. Our results imply that an individual PPV, not CVP, is equivalent to IDVG in assessing volume status after induction. Japanese Society of Anesthesiologists, 2011 Hypovolemia nationallicence Pulse pressure variation nationallicence Initial distribution volume of glucose nationallicence Central venous pressure nationallicence He Zhiyong Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut Qiao Hui Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut Zhou Wei Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut Wang Yun Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut Xu Zhendong Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut Che Xuehua Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut Zhang Jun Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut Liang Weimin Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut Journal of Anesthesia Springer Japan 25/6(2011-12-01), 812-817 0913-8668 25:6<812 2011 25 540 https://doi.org/10.1007/s00540-011-1225-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00540-011-1225-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- He Zhiyong Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Qiao Hui Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Zhou Wei Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Wang Yun Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Xu Zhendong Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Che Xuehua Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Zhang Jun Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Liang Weimin Department of Anesthesiology, Huashan Hospital, Fudan University, No. 12 Urumqi Central Rd., 200040, Shanghai, People's Republic of China aut NATIONALLICENCE 773 0- Journal of Anesthesia Springer Japan 25/6(2011-12-01), 812-817 0913-8668 25:6<812 2011 25 540 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer