caa a22 4500 445373555 CHVBK 20180317142955.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00540-011-1131-6 doi (NATIONALLICENCE)springer-10.1007/s00540-011-1131-6 Time course of changes in cerebral blood flow velocity after tourniquet deflation in patients with diabetes mellitus or previous stroke under sevoflurane anesthesia [Elektronische Daten] [Hiroshi Hinohara, Yuji Kadoi, Kenichiro Takahashi, Shigeru Saito, Chikara Kawauchi, Akio Mizutani] We observed an increase in mean middle cerebral artery blood flow velocity (V mca) after tourniquet deflation during orthopedic surgery under sevoflurane anesthesia in patients with diabetes mellitus or previous stroke. Eight controls, seven insulin-treated diabetic patients, and eight previous stroke patients were studied. Arterial blood pressure, heart rate, V mca, arterial blood gases, and plasma lactate levels were measured every minute for 10min after tourniquet release in all patients. V mca was measured using a transcranial Doppler probe. V mca in all three groups increased after tourniquet deflation, the increase lasting for 4 or 5min. However, the degree of increase in V mca in the diabetic patients was smaller than that in the other two groups after tourniquet deflation (at 2min after tourniquet deflation: control 58.5±3.3, previous stroke 58.4±4.6, diabetes 51.7±2.3; P<0.05 compared with the other two groups). In conclusion, the degree of increase in V mca in diabetic patients is smaller than that in controls and patients with previous stroke. Japanese Society of Anesthesiologists, 2011 Tourniquet nationallicence Orthopedic nationallicence Cerebral blood flow velocity nationallicence Diabetes nationallicence Stroke nationallicence Hinohara Hiroshi Division of Intensive Care, Gunma University Hospital, Maebashi, Japan aut Kadoi Yuji Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-machi, 371-8511, Maebashi, Gunma, Japan aut Takahashi Kenichiro Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-machi, 371-8511, Maebashi, Gunma, Japan aut Saito Shigeru Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-machi, 371-8511, Maebashi, Gunma, Japan aut Kawauchi Chikara Department of Anesthesiology, Gyoda General Hospital, Gyoda, Japan aut Mizutani Akio Department of Anesthesiology, School of Medicine, Oita University, Oita, Japan aut Journal of Anesthesia Springer Japan 25/3(2011-06-01), 409-414 0913-8668 25:3<409 2011 25 540 https://doi.org/10.1007/s00540-011-1131-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00540-011-1131-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hinohara Hiroshi Division of Intensive Care, Gunma University Hospital, Maebashi, Japan aut NATIONALLICENCE 700 1- Kadoi Yuji Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Takahashi Kenichiro Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Saito Shigeru Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Kawauchi Chikara Department of Anesthesiology, Gyoda General Hospital, Gyoda, Japan aut NATIONALLICENCE 700 1- Mizutani Akio Department of Anesthesiology, School of Medicine, Oita University, Oita, Japan aut NATIONALLICENCE 773 0- Journal of Anesthesia Springer Japan 25/3(2011-06-01), 409-414 0913-8668 25:3<409 2011 25 540 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer