caa a22 4500 44537389X CHVBK 20180317142956.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00540-011-1148-x doi (NATIONALLICENCE)springer-10.1007/s00540-011-1148-x Anaphylaxis to pantoprazole during general anesthesia [Elektronische Daten] [Hou-Chuan Lai, Shih-Wei Hsu, Chueng-He Lu, Hsin-I Ma, Chen-Hwan Cherng, Nan-Kai Hung, Ching-Tang Wu] The most frequent causes of anaphylaxis during anesthesia are neuromuscular blocking agents, antibiotics, and latex. Proton pump inhibitors (PPI) are widely used during major surgery for the prevention of stress ulcers, but cases of perioperative anaphylactic reactions to these have rarely been reported. We present a 50-year-old male patient who experienced an episode of anaphylaxis with hypoxemia, hypotension, tachycardia, and generalized erythema after intravenous injection of pantoprazole 40mg and methylprednisolone 1g during general anesthesia. After resuscitation, the patient recovered without any sequelae. Six months after the surgery, a skin test was positive to pantoprazole. Japanese Society of Anesthesiologists, 2011 Anaphylaxis nationallicence Proton pump inhibitors nationallicence Pantoprazole nationallicence Steroid nationallicence Anesthesia nationallicence Lai Hou-Chuan Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, #325, Section2, Chenggung Road, Neihu 114, Taipei, Taiwan, Republic of China aut Hsu Shih-Wei Department of Neurosurgery, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, Republic of China aut Lu Chueng-He Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, #325, Section2, Chenggung Road, Neihu 114, Taipei, Taiwan, Republic of China aut Ma Hsin-I Department of Neurosurgery, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, Republic of China aut Cherng Chen-Hwan Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, #325, Section2, Chenggung Road, Neihu 114, Taipei, Taiwan, Republic of China aut Hung Nan-Kai Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, #325, Section2, Chenggung Road, Neihu 114, Taipei, Taiwan, Republic of China aut Wu Ching-Tang Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, #325, Section2, Chenggung Road, Neihu 114, Taipei, Taiwan, Republic of China aut Journal of Anesthesia Springer Japan 25/4(2011-08-01), 606-608 0913-8668 25:4<606 2011 25 540 https://doi.org/10.1007/s00540-011-1148-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00540-011-1148-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lai Hou-Chuan Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, #325, Section2, Chenggung Road, Neihu 114, Taipei, Taiwan, Republic of China aut NATIONALLICENCE 700 1- Hsu Shih-Wei Department of Neurosurgery, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, Republic of China aut NATIONALLICENCE 700 1- Lu Chueng-He Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, #325, Section2, Chenggung Road, Neihu 114, Taipei, Taiwan, Republic of China aut NATIONALLICENCE 700 1- Ma Hsin-I Department of Neurosurgery, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, Republic of China aut NATIONALLICENCE 700 1- Cherng Chen-Hwan Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, #325, Section2, Chenggung Road, Neihu 114, Taipei, Taiwan, Republic of China aut NATIONALLICENCE 700 1- Hung Nan-Kai Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, #325, Section2, Chenggung Road, Neihu 114, Taipei, Taiwan, Republic of China aut NATIONALLICENCE 700 1- Wu Ching-Tang Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, #325, Section2, Chenggung Road, Neihu 114, Taipei, Taiwan, Republic of China aut NATIONALLICENCE 773 0- Journal of Anesthesia Springer Japan 25/4(2011-08-01), 606-608 0913-8668 25:4<606 2011 25 540 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer