caa a22 4500 445373903 CHVBK 20180317142956.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00540-011-1152-1 doi (NATIONALLICENCE)springer-10.1007/s00540-011-1152-1 Impact of intraoperative hypotension on hospital stay in major abdominal surgery [Elektronische Daten] [Vassilios Tassoudis, George Vretzakis, Argyro Petsiti, Georgia Stamatiou, Katerina Bouzia, Michael Melekos, George Tzovaras] Purpose: Although the relationship between preoperative risk factors and outcomes has been extensively studied, the effect of intraoperative hemodynamic changes in a patient's postoperative course has been less well defined. Methods: We designed a prospective observational study to assess the impact of several variables, and especially hypotension, on postoperative outcome. Patients considered eligible for the study, all more than 18years old, were mentally stable patients scheduled for major abdominal surgery with an expected duration of more than 2h. Total hypotension time (THT), with other variables that possibly influence the outcome, was analyzed using multivariate logistic regression analysis in 100 consecutive patients. Results: Total hypotension time was isolated as a factor significantly associated with morbidity [odds ratio, 5.1 (1.95-13.35)] and significantly prolonged hospital stay [odds ratio, 4.56 (1.85-10.96)]. Patients who had prolonged THT presented more complications (50 vs. 30), especially of the cardiovascular, pulmonary, and gastrointestinal systems. These complications led to delayed hospital discharge in a significant number of patients (36 with THT vs. 17 others). Finally, duration of surgery was associated with postoperative complications [odds ratio, 3.1 (1.2-8.0)]. Conclusion: Persistent hypotension during elective major abdominal surgery is a significant risk factor for postoperative complications and may prolong hospitalization and affect patient outcomes. Anesthetic management for the avoidance of hypotension, as much as possible, during major abdominal surgery may positively affect outcomes. Japanese Society of Anesthesiologists, 2011 Intraoperative hypotension nationallicence Major surgery nationallicence Outcome nationallicence Complications nationallicence Tassoudis Vassilios Department of Anesthesiology, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut Vretzakis George Department of Anesthesiology, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut Petsiti Argyro Department of Anesthesiology, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut Stamatiou Georgia Department of Anesthesiology, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut Bouzia Katerina Department of Anesthesiology, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut Melekos Michael Department of Urology, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut Tzovaras George Department of General Surgery, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut Journal of Anesthesia Springer Japan 25/4(2011-08-01), 492-499 0913-8668 25:4<492 2011 25 540 https://doi.org/10.1007/s00540-011-1152-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00540-011-1152-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tassoudis Vassilios Department of Anesthesiology, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut NATIONALLICENCE 700 1- Vretzakis George Department of Anesthesiology, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut NATIONALLICENCE 700 1- Petsiti Argyro Department of Anesthesiology, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut NATIONALLICENCE 700 1- Stamatiou Georgia Department of Anesthesiology, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut NATIONALLICENCE 700 1- Bouzia Katerina Department of Anesthesiology, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut NATIONALLICENCE 700 1- Melekos Michael Department of Urology, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut NATIONALLICENCE 700 1- Tzovaras George Department of General Surgery, University of Thessaly, Medical School, University Hospital of Larissa, Larissa, Greece aut NATIONALLICENCE 773 0- Journal of Anesthesia Springer Japan 25/4(2011-08-01), 492-499 0913-8668 25:4<492 2011 25 540 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer