caa a22 4500 445373962 CHVBK 20180317142956.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00540-011-1170-z doi (NATIONALLICENCE)springer-10.1007/s00540-011-1170-z Preoperative carbohydrate-rich beverage reduces hypothermia during general anesthesia in rats [Elektronische Daten] [Tomoaki Yatabe, Takashi Kawano, Koichi Yamashita, Masataka Yokoyama] Purpose: Intraoperative hypothermia is associated with several unfavorable events; therefore, it is important to prevent the development of hypothermia. Amino acid consumption and/or infusion have been reported to prevent hypothermia. We hypothesized that preoperative carbohydrate-rich beverage (Arginaid Water™) loading can reduce intraoperative hypothermia in rats under general anesthesia. Methods: We divided 18 rats into 3 groups (group A, 8mL/kg of saline; group B, 8mL/kg of a carbohydrate-rich beverage; and group C, 21mL/kg of the carbohydrate-rich beverage). The rats were administered each beverage at the abovementioned doses via an oral gastric tube 30min before the induction of anesthesia. During the 2-h general anesthesia, rectal temperature was measured at 20-min intervals. Serum ketone body concentration was measured at 0 and 120min. Results: The baseline temperature was not significantly different among the groups. At the end of the experiment, group A showed a significantly greater decrease in temperature from the baseline (5.4±0.8°C) than group B (3.9±0.7°C, P=0.01) and group C (3.8±0.8°C, P=0.01). The temperatures in groups B and C were not significantly different. There was no significant change in the serum ketone body concentration from the baseline at the end of the experiment in group A. However, the serum ketone body concentrations in group B and group C were significantly decreased from the baseline. Conclusion: Preoperative carbohydrate loading reduces hypothermia in rats under general anesthesia. Japanese Society of Anesthesiologists, 2011 Preoperative carbohydrate loading nationallicence Enhanced recovery after surgery (ERAS) nationallicence Intraoperative hypothermia nationallicence General anesthesia nationallicence Yatabe Tomoaki Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu Oko-cho, 783-8505, Nankoku, Kochi, Japan aut Kawano Takashi Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu Oko-cho, 783-8505, Nankoku, Kochi, Japan aut Yamashita Koichi Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu Oko-cho, 783-8505, Nankoku, Kochi, Japan aut Yokoyama Masataka Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu Oko-cho, 783-8505, Nankoku, Kochi, Japan aut Journal of Anesthesia Springer Japan 25/4(2011-08-01), 558-562 0913-8668 25:4<558 2011 25 540 https://doi.org/10.1007/s00540-011-1170-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00540-011-1170-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yatabe Tomoaki Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu Oko-cho, 783-8505, Nankoku, Kochi, Japan aut NATIONALLICENCE 700 1- Kawano Takashi Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu Oko-cho, 783-8505, Nankoku, Kochi, Japan aut NATIONALLICENCE 700 1- Yamashita Koichi Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu Oko-cho, 783-8505, Nankoku, Kochi, Japan aut NATIONALLICENCE 700 1- Yokoyama Masataka Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu Oko-cho, 783-8505, Nankoku, Kochi, Japan aut NATIONALLICENCE 773 0- Journal of Anesthesia Springer Japan 25/4(2011-08-01), 558-562 0913-8668 25:4<558 2011 25 540 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer