caa a22 4500 445374349 CHVBK 20180317142958.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00540-011-1200-x doi (NATIONALLICENCE)springer-10.1007/s00540-011-1200-x Influence of tidal volume for stroke volume variation to predict fluid responsiveness in patients undergoing one-lung ventilation [Elektronische Daten] [Koichi Suehiro, Ryu Okutani] We designed this study to determine the predictive value for fluid responsiveness of stroke volume variation (SVV) in patients undergoing one-lung ventilation (OLV), ventilated at different tidal volumes. All patients scheduled for pulmonary lobectomy were randomized into two groups according to their tidal volume [group H: tidal volume 8ml/kg (n=36); group L: tidal volume 6ml/kg (n=37)]. After starting OLV, volume loading was performed by administration of 500ml 6% hydroxyethylated starch for 30min. Hemodynamic variables were measured before and after volume loading using the Vigileo-FloTrac system. Patients in both groups were divided into fluid responders and non-responders, and responders were defined as those who demonstrated an increase in cardiac index ≥15% after volume expansion. The area under the receiver operating characteristic curve for SVV to discriminate between responders and non-responders was 0.776 in group H and 0.648 in group L. The optimal threshold value of SVV was 10.5% (sensitivity, 85.7%; specificity, 66.7%) in group H and 8% (sensitivity, 69.5%; specificity, 64.3%) in group L. We found that SVV could predict fluid responsiveness in patients undergoing OLV with acceptable levels of sensitivity and specificity only when tidal volume is at least 8ml/kg. Japanese Society of Anesthesiologists, 2011 Stroke volume variation nationallicence One-lung ventilation nationallicence Preload nationallicence Vigileo-FloTrac system nationallicence Tidal volume nationallicence Suehiro Koichi Department of Anesthesiology, Osaka City General and Children's Hospital, 2-13-22 Miyakojima-hondori, Miyakojimaku, 534-0021, Osaka, Osaka, Japan aut Okutani Ryu Department of Anesthesiology, Osaka City General and Children's Hospital, 2-13-22 Miyakojima-hondori, Miyakojimaku, 534-0021, Osaka, Osaka, Japan aut Journal of Anesthesia Springer Japan 25/5(2011-10-01), 777-780 0913-8668 25:5<777 2011 25 540 https://doi.org/10.1007/s00540-011-1200-x text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00540-011-1200-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Suehiro Koichi Department of Anesthesiology, Osaka City General and Children's Hospital, 2-13-22 Miyakojima-hondori, Miyakojimaku, 534-0021, Osaka, Osaka, Japan aut NATIONALLICENCE 700 1- Okutani Ryu Department of Anesthesiology, Osaka City General and Children's Hospital, 2-13-22 Miyakojima-hondori, Miyakojimaku, 534-0021, Osaka, Osaka, Japan aut NATIONALLICENCE 773 0- Journal of Anesthesia Springer Japan 25/5(2011-10-01), 777-780 0913-8668 25:5<777 2011 25 540 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer