caa a22 4500 445374551 CHVBK 20180317142958.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00540-010-1088-x doi (NATIONALLICENCE)springer-10.1007/s00540-010-1088-x Adequacy of control of preoperative hypertension can affect landiolol-induced hemodynamic changes in elderly patients during emergence from anesthesia [Elektronische Daten] [Yuji Kadoi, Tatsuo Horiuchi, Shinya Uchida, Shigeru Saito] We examined the dose-related effects of landiolol on hemodynamics during emergence from anesthesia of elderly patients with uncontrolled hypertension. Thirty-three normotensive, 34 controlled hypertensive, and 31 uncontrolled hypertensive elderly patients were divided into three groups: control (saline infusion), 0.125 landiolol group, and 0.25 landiolol group. Landiolol or saline infusion was administered at 0.125 (0.125 landiolol group) or 0.25 (0.25 landiolol group) mg/kg/min for 1min and thereafter decreased to 0.04 or 0.08mg/kg/min, respectively, until extubation, under regular heart rate and blood pressure monitoring. In normotensive patients, the 0.125mg/kg/min landiolol infusion was suitable for stabilization of systolic blood pressure and heart rate during tracheal extubation. Controlled hypertensive patients required a 0.25mg/kg/min landiolol infusion for stabilization of systolic blood pressure and heart rate during tracheal extubation. In uncontrolled hypertensive patients the 0.25mg/kg/min landiolol infusion could stabilize heart rate, but not systolic blood pressure. In conclusion, the adequacy of preoperative hypertensive control could affect landiolol infusion-induced hemodynamic stability during emergence of elderly patients from anesthesia. Japanese Society of Anesthesiologists, 2011 Emergence period nationallicence Landiolol nationallicence Heart rate nationallicence Elderly nationallicence Hypertension nationallicence Kadoi Yuji Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Horiuchi Tatsuo Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Uchida Shinya Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Saito Shigeru Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Journal of Anesthesia Springer Japan 25/2(2011-04-01), 271-277 0913-8668 25:2<271 2011 25 540 https://doi.org/10.1007/s00540-010-1088-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00540-010-1088-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kadoi Yuji Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Horiuchi Tatsuo Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Uchida Shinya Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Saito Shigeru Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 773 0- Journal of Anesthesia Springer Japan 25/2(2011-04-01), 271-277 0913-8668 25:2<271 2011 25 540 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer