caa a22 4500 445374691 CHVBK 20180317142959.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00540-011-1095-6 doi (NATIONALLICENCE)springer-10.1007/s00540-011-1095-6 Use of rocuronium-sugammadex, an alternative to succinylcholine, as a muscle relaxant during electroconvulsive therapy [Elektronische Daten] [Hiroko Hoshi, Yuji Kadoi, Jiro Kamiyama, Akiko Nishida, Hiroyuki Saito, Masaki Taguchi, Shigeru Saito] We compared the recovery time from neuromuscular blockade induced by rocuronium combined with sugammadex versus succinylcholine during electroconvulsive therapy (ECT). Anesthesia was induced using propofol, followed by succinylcholine (1mg/kg) or rocuronium (0.6mg/kg). Immediately after the seizure stopped, 16mg/kg sugammadex was infused. Neuromuscular monitoring was performed and continued until recovery of the train-of-four ratio to 0.9. We compared the recovery time of T1 to 10 and 90% between groups. Patients were also assessed for clinical signs, such as time to first spontaneous breath from the administration of muscle relaxant and eye opening to verbal commands. Although recovery time of T1 to 10 and 90% in the rocuronium-sugammadex group was shorter than in the succinylcholine group, the difference was not statistically significant. Further, the seizure duration with succinylcholine (33±8s) was shorter than that with rocuronium-sugammadex (39±4s). In conclusion, this study demonstrates the potential benefit of use of rocuronium-sugammadex as an alternative to succinylcholine for muscle relaxation during ECT. Japanese Society of Anesthesiologists, 2011 Electroconvulsive therapy nationallicence Muscle relaxant nationallicence Rocuronium nationallicence Sugammadex nationallicence Succinylcholine nationallicence Hoshi Hiroko Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Kadoi Yuji Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Kamiyama Jiro Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Nishida Akiko Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Saito Hiroyuki Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Taguchi Masaki Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Saito Shigeru Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut Journal of Anesthesia Springer Japan 25/2(2011-04-01), 286-290 0913-8668 25:2<286 2011 25 540 https://doi.org/10.1007/s00540-011-1095-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00540-011-1095-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hoshi Hiroko Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Kadoi Yuji Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Kamiyama Jiro Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Nishida Akiko Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Saito Hiroyuki Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Taguchi Masaki Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Saito Shigeru Department of Anesthesiology, Gunma University, School of Medicine, 3-39-22 Showa-Machi, 371-8511, Maebashi, Gunma, Japan aut NATIONALLICENCE 773 0- Journal of Anesthesia Springer Japan 25/2(2011-04-01), 286-290 0913-8668 25:2<286 2011 25 540 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer