caa a22 4500 445374748 CHVBK 20180317142959.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00540-011-1092-9 doi (NATIONALLICENCE)springer-10.1007/s00540-011-1092-9 The effect of ketamine on tracheal intubating conditions without neuromuscular blockade during sevoflurane induction in children [Elektronische Daten] [Kyong Kim, Hyun Kwak, Sang Min, Sook Lee, Kyung Kim, Jong Kim] Purpose: The purpose of this study was to investigate the effect of ketamine on intubating conditions for tracheal intubation during anesthesia induction with sevoflurane and alfentanil in pediatric patients. Methods: After obtaining parental consents, 50 children, aged 3-10years, were randomly allocated into two groups to receive either i.v. ketamine 0.5mg/kg (ketamine group, n=25) or i.v. saline 5ml (control saline group, n = 25). One minute after injection of the study drug (ketamine or saline), anesthesia was induced with 5% sevoflurane, followed by injection of alfentanil 10μg/kg 1min later. The trachea was intubated 4min after inhalational induction of anesthesia. Acceptable intubation was defined as excellent or good intubating conditions. Mean arterial pressure (MAP) and heart rate (HR) were recorded during the induction period. Results: The percentage of patients with acceptable intubating conditions was higher in the ketamine group (87%) than in the control group (52%) (P=0.0129). MAP before intubation was significantly lower in the control group than in the ketamine group (P=0.001). Conclusion: This study demonstrated that administration of ketamine 0.5mg/kg could improve intubating conditions for tracheal intubation without neuromuscular blockade and preserve hemodynamic stability during sevoflurane inhalation induction with alfentanil in children. Japanese Society of Anesthesiologists, 2011 Inhaled anesthetics nationallicence Ketamine nationallicence Tracheal intubating conditions nationallicence Kim Kyong Department of Anesthesiology and Pain Medicine, Himchan Hospital, Incheon, Korea aut Kwak Hyun Department of Anesthesiology and Pain Medicine, Gachon University of Medicine and Science, Gil Medical Center, Incheon, Korea aut Min Sang Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, San 5, Wonchon-dong, Yeongtong-gu, 443-721, Suwon, Korea aut Lee Sook Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, San 5, Wonchon-dong, Yeongtong-gu, 443-721, Suwon, Korea aut Kim Kyung Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, San 5, Wonchon-dong, Yeongtong-gu, 443-721, Suwon, Korea aut Kim Jong Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, San 5, Wonchon-dong, Yeongtong-gu, 443-721, Suwon, Korea aut Journal of Anesthesia Springer Japan 25/2(2011-04-01), 195-199 0913-8668 25:2<195 2011 25 540 https://doi.org/10.1007/s00540-011-1092-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00540-011-1092-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kim Kyong Department of Anesthesiology and Pain Medicine, Himchan Hospital, Incheon, Korea aut NATIONALLICENCE 700 1- Kwak Hyun Department of Anesthesiology and Pain Medicine, Gachon University of Medicine and Science, Gil Medical Center, Incheon, Korea aut NATIONALLICENCE 700 1- Min Sang Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, San 5, Wonchon-dong, Yeongtong-gu, 443-721, Suwon, Korea aut NATIONALLICENCE 700 1- Lee Sook Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, San 5, Wonchon-dong, Yeongtong-gu, 443-721, Suwon, Korea aut NATIONALLICENCE 700 1- Kim Kyung Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, San 5, Wonchon-dong, Yeongtong-gu, 443-721, Suwon, Korea aut NATIONALLICENCE 700 1- Kim Jong Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, San 5, Wonchon-dong, Yeongtong-gu, 443-721, Suwon, Korea aut NATIONALLICENCE 773 0- Journal of Anesthesia Springer Japan 25/2(2011-04-01), 195-199 0913-8668 25:2<195 2011 25 540 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer