caa a22 4500 44537621X CHVBK 20180317143003.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00702-010-0556-7 doi (NATIONALLICENCE)springer-10.1007/s00702-010-0556-7 High frequency deep brain stimulation of the subthalamic nucleus versus continuous subcutaneous apomorphine infusion therapy: a review [Elektronische Daten] [R. Carron, V. Fraix, C. Maineri, E. Seigneuret, B. Piallat, P. Krack, P. Pollak, A. Benabid, Stéphan Chabardès] In advanced Parkinson's disease, several therapeutical option including not only lesional surgery (VIM, GPi) and deep brain stimulation (STN, GPi, VIM) but also continuous subcutaneous apomorphine infusion therapy can be proposed to the patient. The choice depends on the hope of the patient, patient's general health condition and the experience and choice of the neurosurgical and neurologist team. Here we report our experience based on 400 STN-DBS cases and we discuss, on the basis of our experience and on the literature, the advantage and disadvantage of DBS strategy as compared with non-surgical option such as continuous subcutaneous apomorphine infusion therapy. Springer-Verlag, 2010 Subthalamic nucleus nationallicence Deep brain stimulation nationallicence Advanced Parkinson's disease nationallicence Apomorphine nationallicence Dopa therapy nationallicence Carron R. Department of Neurosurgery, University Hospital, Grenoble, France aut Fraix V. Department of Neurology, University Hospital, Grenoble, France aut Maineri C. Department of Neurosurgery, University Hospital, Grenoble, France aut Seigneuret E. Department of Neurosurgery, University Hospital, Grenoble, France aut Piallat B. Grenoble Institute of Neuroscience, INSERM U836, Grenoble, France aut Krack P. Department of Neurology, University Hospital, Grenoble, France aut Pollak P. Department of Neurology, University Hospital, Grenoble, France aut Benabid A. CEA LETI Clinatec, Grenoble, France aut Chabardès Stéphan Department of Neurosurgery, University Hospital, Grenoble, France aut Journal of Neural Transmission Springer Vienna 118/6(2011-06-01), 915-924 0300-9564 118:6<915 2011 118 702 https://doi.org/10.1007/s00702-010-0556-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00702-010-0556-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Carron R. Department of Neurosurgery, University Hospital, Grenoble, France aut NATIONALLICENCE 700 1- Fraix V. Department of Neurology, University Hospital, Grenoble, France aut NATIONALLICENCE 700 1- Maineri C. Department of Neurosurgery, University Hospital, Grenoble, France aut NATIONALLICENCE 700 1- Seigneuret E. Department of Neurosurgery, University Hospital, Grenoble, France aut NATIONALLICENCE 700 1- Piallat B. Grenoble Institute of Neuroscience, INSERM U836, Grenoble, France aut NATIONALLICENCE 700 1- Krack P. Department of Neurology, University Hospital, Grenoble, France aut NATIONALLICENCE 700 1- Pollak P. Department of Neurology, University Hospital, Grenoble, France aut NATIONALLICENCE 700 1- Benabid A. CEA LETI Clinatec, Grenoble, France aut NATIONALLICENCE 700 1- Chabardès Stéphan Department of Neurosurgery, University Hospital, Grenoble, France aut NATIONALLICENCE 773 0- Journal of Neural Transmission Springer Vienna 118/6(2011-06-01), 915-924 0300-9564 118:6<915 2011 118 702 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer